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Endemic Goitre in the Union of South Africa and Some Neighbouring Territories.
Authors: Douw G. Steyn, B.Sc., Dr. Med. Vet. (Vienna), D.V.Sc., Professor of Pharmacology, Medical Faculty, University of Pretoria; J. Kieser, Artseksamen (M.D.), former Chief Medical Inspector of Schools, Transvaal Provincial Administration; W.A. Odendaal, D.Sc., Research Officer in Nutrition, Union Department of Nutrition, Pretoria; H. Malherbe, M.A., M.B.Ch.B., Senior Medical Officer, Poliomyelitis Research Foundation, South
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Moderating Role of TSHR and PTPN22 Gene Polymorphisms in Effects of Excessive Fluoride on Thyroid: a School-Based Cross-Sectional Study.
We aimed to investigate the relationship between the effects excessive of fluoride on thyroid health in children and the moder- ating role of thyroid stimulating hormone receptor (TSHR) or protein tyrosine phosphatase nonreceptor-22 (PTPN22) gene polymorphisms. Four hundred thirteen children (141 with dental fluorosis and 198 boys) were enrolled from
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[Premature aging of the population in the zone of endemic goiter.]
Original title: Prezhdevremennoe starenie naseleniya v zone rasprostraneniya endemicheskogo zoba. No Abstract
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Prevalence and manifestations of water-born fluorosis among schoolchildren in Kaiwara village of India: a preliminary study
Background: Fluorosis is an endemic condition with prevalence in 19 states and union territories in India. It is an urgent task to survey the fluorosis-related problems in these regions. Objective: To study the clinical manifestations of water-born fluorosis among schoolchildren in Kaiwara village of India. Methods: A cross-sectional study was conducted in
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Goitre in school girls of the Mewat area of Haryana
A survey was carried out on 5449 school girls aged 10-16 years in the Mewat area of Haryana for goitre. The overall prevalence of goitre was nearly 29.5%. Thus goitre was a public health problem in the region. Analysis of the water sources in the study population used for drinking
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Fluoride & Goiter
Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the
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Fluorine in the Aetiology of Endemic Goitre
The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.
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The Relationship Between Fluoride Exposure & Goitre in South Africa
As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.
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Fluoride, Water Hardness, and Endemic Goitre
Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.
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Fluoride Exposure Aggravates the Impact of Iodine Deficiency
A consistent body of animal and human research shows that fluoride exposure worsens the impact of an iodine deficiency. Iodine is the basic building block of the T3 and T4 hormones and thus an adequate iodine intake is essential for the proper functioning of the thyroid gland. When iodine intake is inadequate during infancy and
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