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  • Functional state of thyroid under extended exposure to fluorides

    The issue of specific effect of fluorine on the thyroid in humans remains debatable. There is no doubt, however, that cases of experimental fluorosis are characterized by specific toxicity of fluorine to the thyroid. The hypoactivity of thyroid epithelium is observed, the destructive changes in the follicular cells increasing with the

  • Epidemiological study of goitre in endemic fluorosis district of Gujarat

    Soft tissue fluoride toxicity is well established. Several animal and human studies of the effect of fluoride on the thyroid gland have shown conflicting results. Endemic fluorosis and goitre are widespread in India with considerable overlapping in different geographical zones. We examined 22,276 individuals for  presence of goitre and dental

  • [A preliminary approach to the relationship of both endemic goiter and fluorosis in the valley of Manasi River, Xin-Jiang to environmental geochemistry].

    According to the geographical features of the inland basins and the motion law by which a variety of chemical elements move along the rivers and deposit in the bottom of the basins in Xinjiang,the author made a series of investigations to find out the effects of the factors of environmental

  • Endemic Goitre in the Union of South Africa and Some Neighbouring Territories.

    Authors: Douw G. Steyn, B.Sc., Dr. Med. Vet. (Vienna), D.V.Sc., Professor of Pharmacology, Medical Faculty, University of Pretoria; J. Kieser, Artseksamen (M.D.), former Chief Medical Inspector of Schools, Transvaal Provincial Administration; W.A. Odendaal, D.Sc., Research Officer in Nutrition, Union Department of Nutrition, Pretoria; H. Malherbe, M.A., M.B.Ch.B., Senior Medical Officer, Poliomyelitis Research Foundation, South

  • Fluorine in the aetiology of endemic goitre

    MANY different factors leading to relative or absolute deficiency of iodine may cause changes in the thyroid gland. May (1935) found that the administration of fluorine to rats produced hypoplasia of the thyroid epithelium with altered staining reaction of the colloid. Having experimented with over 800 patients, he advocated internal

• Related FAN Content :

  • The Relationship Between Fluoride Exposure & Goitre in South Africa

    As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.

  • Fluorine in the Aetiology of Endemic Goitre

    The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.

  • Fluoride & Goiter

    Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the

  • Fluoride, Water Hardness, and Endemic Goitre

    Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.

  • Mikhailets (1996): Functional state of thyroid under extended exposure to fluorides

    Abnormalities in the thyroid function characterized by a decreased iodine absorption function of the thyroid, a low level T3 syndrome, and a slight increase of the TSH level are observed in cases of chronic fluorine intoxication in the industrial workers.