Abstract
The prevalence of goitre in 17 Himalayan villages has been estimated. Water-samples from each village were taken, and levels of iodine, fluoride, and hardness determined. In 13 villages wide variations in goitre prevalence were not attributable to differences in iodine intake, which remained constant within a narrow range. Instead, variations in goitre prevalence were found to correlate closely with the fluoride content (?=0·74; P<0·01) and with the hardness (?=0·77; P<0·01) of the water in each village. The effects of fluoride and water hardness seem to be independent.
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[Effects of fluoride on thyroid structure in chicks].
Objective: To investigate the effects of fluoride on thyroid structure in chicks. Methods: 250 one day chicks were randomly divided into 5 groups, 50 for each. Group I was the control, and other four groups, group II, III, IV, V were fed the diets containing 500, 1,000, 1,500, 2,000 mg/kg of
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Long-term effects of various iodine and fluorine doses on the thyroid and fluorosis in mice
OBJECTIVE: To elucidate the participation of the independent and combined long term effect of various concentrations of iodine and fluorine on the pathogenesis of goiter and fluorosis in mice. METHODS: Nine drinking water supplies with different iodine and fluorine content were prepared by combination of potassium iodate and sodium fluoride solutions in bidistilled
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Fluorine and thyroid gland function: a review of the literature
The increasing use of fluoride for prevention of dental caries poses the problem as to whether this halogen has antagonistic properties towards iodine, whereby it could hamper the success of iodine prophylaxis of endemic goitre. Review of the literature shows that some authors have found an inhibition by fluoride of
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A survey of goiter morbidity in Ban Mae Toen, Northwest Thailand
A number of cases of goiter have been reported from Ban Mae Toen (BMT) northwestern Thailand, therefore we carried out this study to evaluate the prevalence and severity of goiter in BMT. We suspected fluoride toxicity as a factor in this phenomenon, therefore we used a WHO model using photographs
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[Iodized-fluoridized salt for the prevention of goiter and caries].
No abstract available
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Fluorine in the Aetiology of Endemic Goitre
The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.
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The Relationship Between Fluoride Exposure & Goitre in South Africa
As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.
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Fluoride & Goiter
Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the
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Fluoride, Water Hardness, and Endemic Goitre
Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.
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Fluoride's Impact on Thyroid Hormones
Up through the 1950s, doctors in Europe and South America prescribed fluoride for this purpose in patients with hyperthyroidism. (Merck Index 1968). Fluoride was selected as a thyroid suppressant based on findings dating back to the mid-19th century that fluoride is a goitrogen (a substance that can cause goiter). When used as
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