Abstract
Blood and urine were collected from 72 cows in six dairy herds with varying severity of dental and bone fluorotic lesions. Urinary fluoride averaged 5.13 ppm and ranged from 1.04 to 15.7 ppm fluoride. Thyroxine and triiodothyronine in serum decreased with increasing urinary fluoride, eosinophils increased, and cholesterol tended to decrease. Cattle afflicted with fluorosis developed hypothyroidism, anemia, and eosinophilia of leukocytes. Bone ash averaged 2400 ppm fluoride in 22 specimens from eight herds (range 850 to 6935 ppm fluoride). Mineral supplements were the main sources of excess fluoride. Fluoride lesions were on some cows of all herds suggesting that fluoride may affect the health and performance of some cows in “normal” herds. Fluoride lesions were on young cattle and calves in fluorosis herds.
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Fluoride in Drinking Water: A Scientific Review of EPA’s Standards.
Excerpts: Summary Under the Safe Drinking Water Act, the U.S. Environmental Protection Agency (EPA) is required to establish exposure standards for contaminants in public drinking-water systems that might cause any adverse effects on human health. These standards include the maximum contaminant level goal (MCLG), the maximum contaminant level (MCL), and the secondary
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Necessity to Pay Attention to the Effects of Low Fluoride on Human Health: an Overview of Skeletal and Non-skeletal Damages in Epidemiologic Investigations and Laboratory Studies.
Due to the implementation of water improvement and fluoride reduction plans supported by central and local governments in recent years, areas with high fluoride exposure are being gradually decreased. Therefore, it is of practical importance to study the effect of low fluoride on human health. Epidemiologic investigations and in vivo
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Investigations of soft tissue functions in fluorotic individuals of North Gujurat
The present study was undertaken to investigate the various health problems caused by water-borne fluoride in endemic villages of Mehsana and Banaskantha districts of Gujarat. The study revealed high levels of fluoride in serum samples of the villagers. Mottling of teeth and skeletal complications were common. Intake of fluoride caused
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Effects of addition of fluorine in diets differing in protein content on urinary fluoride excretion, clinical chemistry and thyroid hormones in calves
In order to compare the effects of addition of fluorine (F) in diets differing in protein content on the urinary F excretion, blood profile and thyroid hormones, 30 crossbred calves (6-8 months) initially exposed to different protein levels were allotted into six groups in a 3 × 2 factorial design. The factors
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Fluoride augments the mitogenic and antigenic response of human blood lymphocytes in vitro
It has been shown that fluoride, the agent responsible for reduction of dental caries worldwide and a recognized proliferative agent, is an adjuvant when given intragastrically to rats. Furthermore, plasma fluoride levels increase in humans after various fluoride treatments. The studies presented here show that fluoride also has the ability
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Fluoride & Goiter
Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the
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Fluoride & the Immune System - Summation from the US National Research Council (2006)
“There is no question that fluoride can affect the cells involved in providing immune responses. The question is what proportion, if any, of the population consuming drinking water containing fluoride at 4.0 mg/L on a regular basis will have their immune systems compromised? Not a single epidemiologic study has investigated whether fluoride in the drinking water at 4 mg/L is associated with changes in immune function. Nor has any study examined whether a person with an immunodeficiency disease can tolerate fluoride ingestion from drinking water.”
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Fluoride Aggravates Thyroid Damage Caused by Excess Iodine Intake
Chinese researchers have found that the combination of excess fluoride with excess iodine caused greater reductions in IQ, or greater increases in goitre than either scenario by itself.
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Is fluoride-induced hyperthyroidism a cause of psychosis among East African immigrants to Scandinavia?
When people with a compensated fluoride-induced hypothyroidism move to a low-fluoride area, the fluoride-induced inhibition of the production of thyroid hormones ceases. In Scandinavia, the dietary intake of iodine is usually quite high due to iodized table salt and easy access to marine fish. Under these conditions, the elevated capacity for production of thyroid hormones may result in hyperthyroidism.
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Fluoride Exposure Aggravates the Impact of Iodine Deficiency
A consistent body of animal and human research shows that fluoride exposure worsens the impact of an iodine deficiency. Iodine is the basic building block of the T3 and T4 hormones and thus an adequate iodine intake is essential for the proper functioning of the thyroid gland. When iodine intake is inadequate during infancy and
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