Abstract
The author presents evidence of damage to the spinal cord in skeletal fluorosis. Since pressure on the cord by osteophytes was ruled out, direct action of fluoride on cord tissue is likely to be responsible for this condition.
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Comparative study on the influence of fluoride on lipid peroxidation and antioxidants levels in the different brain regions of well-fed and protein undernourished rats.
Effects of fluoride on the levels of Lipid peroxidation (LP) and antioxidant enzymes in the brain regions of protein undernourished (PU) and well-fed rats (WF) rats exposed to 100 ppm fluoride in drinking water were investigated. The results indicate that the mean body weights and the total brain weights of
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Effect of fluoride on the proteomic profile of the hippocampus in rats
Two-dimensional gel electrophoresis (2-DE) was used to detect fluoride-induced alterations in the proteome of the rat hippocampus. Male Sprague-Dawley rats (n=30) were subjected to treatments three weeks after weaning. Animals of the first group were injected intraperitoneally (i.p.) with aqueous NaF (20 mg/kg/body weight/day), the second group, injected with physiological
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Aluminum and fluoride impacts cortex and hippocampus structure in rats: protective role of resveratrol.
Metals such as aluminum and Fluoride have been implicated in the etiology of several neurodegenerative disorders . Resveratrol, a natural polyphenol, exerting a wide range of biological and pharmacological activities including its antioxidative properties against neurodegenerative disorders through its ability to lessen oxidative stress. Rats were divided in to 4
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Histopathological investigation of fluoride-induced neurotoxicity in rabbits.
SUMMARY: Brain tissues for neurohistopathological study were obtained at autopsy from albino rabbits that had been subcutaneously injected for 15 weeks with 0, 5, 10, 20, and 50 mg of sodium fluoride in 1 mL of aqueous solu- tions/kg bw/day. Neuropathological changes occurred with loss of the mo- lecular layer and glial cell layer
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Histopathological investigation of fluoride-induced neurotoxicity in rabbits
Brain tissues for neurohistopathological study were obtained at autopsy from albino rabbits that had been subcutaneously injected for 15 weeks with 0, 5, 10, 20, and 50 mg sodium fluoride in 1 mL of aqueous solutions/kg bw/day. Neuropathological changes occurred with loss of the molecular layer and glial cell layer
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Fluoride Affects Learning & Memory in Animals
An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out
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Fluoride & IQ: The 65 Studies
As of May 2020, a total of 73 studies have investigated the relationship between fluoride and human intelligence. Of these investigations, 65 studies have found that elevated fluoride exposure is associated with reduced IQ in humans, while over 60 animal studies have found that fluoride exposure impairs the learning and/or
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Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
The NRC's analysis on fluoride and the brain.
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
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