Abstract
Sixty-six eastern screech-owls (Otus asio) were paired and randomly assigned to dietary treatment groups of 0, 40, or 200 ppm (mg/kg) fluoride (as sodium fluoride) in November 1981. Hatching success was adversely affected at the 200 ppm (mg/kg) level, suggesting potential detrimental impacts to wild populations exposed to fluoride pollution. Eggshell thickness was unaffected. Although fluoride concentrations were elevated in bone and eggshells, large variations among individuals were observed as well as a trend for eggshell residues to increase with sequence of laying. Females had higher residues of fluoride in bone than males. Although fluoride levels in bone and eggshells are useful indicators of exposure, the variability in residues among individuals makes residue data from field collections of limited usefulness in assessing hazards in wild birds.
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Vitamin D ameliorates fluoride-induced embryotoxicity in pregnant rats
We have evaluated the ameliorative effect of vitamin D on fluoride-induced embryotoxicity in pregnant rats. Oral administration of sodium fluoride (NaF; 40 mg/kg body weight) from days 6 to 19 of gestation caused, as compared with control, significantly lowered body weight, feed consumption, absolute uterine weight and number of implantations.
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Combination of fluoride and endosulfan induced teratogenicity and developmental toxicity in Swiss albino mice exposed during organogenesis.
The present investigation was conducted to evaluate the teratogenic and developmental toxicity of fluoride and endosulfan alone and in combination in pregnant Swiss albino mice exposed during the organogenetic period (5-14 days) of gestation. Fluoride (25.1 mg/kg body weight in water) and endosulfan (1.8 mg/kg bw by oral intubation) when
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Relationship between municipal water fluoridation and preterm birth in Upstate New York
The annual incidence of preterm birth (PTB) (<37 weeks gestation) in the United States is approximately 10% and is associated with considerable morbidity and mortality. Current literature suggests an association between periodontal disease and PTB. Domestic water fluoridation is thought to have lessened the burden of dental disease. Theoretically, one
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Effective interventional approach to control anaemia in pregnant women
Anaemia in pregnancy and low birth weight babies, a serious public health problem, troubles India and several other nations. This article reports the results of a approach to address the issue. Women up to 20 week pregnancy with haemoglobin (Hb) 9.0 g/dl or less, those with urinary fluoride beyond 1.0
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Fetotoxicity of fluoride in rats and the protective action of some antioxidants
The aim of this study was to assess the efficacy of antioxidants to prevent or alleviate fluoride (F) toxicity in pregnant female Wistar rats and their fetuses. Groups of pregnant rats (10 in each group) were treated by oral intubation with F (40 mg F – /kg bw/day from NaF),
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Dental Fluorosis & Enamel Hypoplasia in Children with Kidney Disease
Children with kidney disease are known to have high levels of fluoride in their blood and to be at risk for disfiguring tooth defects. Research suggests that high levels of fluoride in blood, which can cause the tooth defect known as dental fluorosis, can contribute to the defects that occur
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Fluoridation, Dialysis & Osteomalacia
In the 1960s and 1970s, doctors discovered that patients receiving kidney dialysis were accumulating very high levels of fluoride in their bones and blood, and that this exposure was associated with severe forms of osteomalacia, a bone-softening disease that leads to weak bones and often excruciating bone pain. Based on
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Skeletal Fluorosis & Individual Variability
One of the common fallacies in the research on skeletal fluorosis is the notion that there is a uniform level of fluoride that is safe for everyone in the population. These "safety thresholds" have been expressed in terms of (a) bone fluoride content, (b) daily dose, (c) water fluoride level, (d) urinary fluoride level, and (e) blood fluoride level. The central fallacy with each of these alleged safety thresholds, however, is that they ignore the wide range of individual susceptibility in how people respond to toxic substances, including fluoride.
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Mayo Clinic: Fluoridation & Bone Disease in Renal Patients
The available evidence suggests that some patients wtih long-term renal failure are being affected by drinking water with as little as 2 ppm fluoride. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers and if fluoride is indeed the cause. It would seem prudent, therefore, to monitor the fluoride intake of patients with renal failure living in high fluoride areas.
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Annapolis: Water Fluoridation Linked to Death of Dialysis Patient
EVENING CAPITAL (Annapolis, Maryland) November 29, 1979 Fluoride Linked to Death by Mary Ann Kryzankowicz Staff Writer Fluoride poisoning has been definitely linked to the death of a 65-year-old kidney dialysis patient who became ill during a blood cleaning process Nov 11. State Medical Examiner Dr. (illegible) Guard has ruled that Lawrence Blake, 65, of Arundel
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