Abstract
Gastroscopy to 35 patients with fluorosis, 32 with arsenic-fluorosis, and 25 control had been performed to study the influence of fluorosis on arsenic-fluorosis on the gastric mucosa. There was significant difference on gradient and activity of chronic gastritis among the three groups, but there was no significant difference in the fluorosis and arsenic-fluorosis [groups]. It appears that pathological changes of gastric mucosa of fluorosis and arsenic-fluorosis may be caused only by fluorosis.
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Evaluation of kidney injury biomarkers in an adult Mexican population environmentally exposed to fluoride and low arsenic levels.
Highlights Fluoride exposure increased renal injury biomarkers (ALB, Cys-C, KIM-1 and OPN). Fluoride could be considered an environmental kidney toxicant. Exposure to low concentrations of arsenic does not increase kidney injury biomarkers. Co-exposure to low arsenic level does not enhanced renal fluoride toxicity. Fluoride (F) is a toxicant widely distributed
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Fluoride and arsenic exposure impairs learning and memory and decreases mGluR5 expression in the hippocampus and cortex in rats.
Fluoride and arsenic are two common inorganic contaminants in drinking water that are associated with impairment in child development and retarded intelligence. The present study was conducted to explore the effects on spatial learning, memory, glutamate levels, and group I metabotropic glutamate receptors (mGluRs) expression in the hippocampus and cortex
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Level of fluoride and arsenic in household shallow well water in Wamiao and Xinhuai villages in Jiangsu Province, China
After previously excluding iodine and lead as confounding factors, the aim of the present study, conducted in June 2013, was to consider whether arsenic was a confounding factor in the studies of children’s intelligence in Wamiao and Xinhuai. Fluoride and arsenic levels were measured in water samples from the 37
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Influence of fluoride exposure on reaction time and visuospatial organization in children
Fluoride exposure is an important public health problem in several Mexican states. In the city of San Luis Potosi, Mexico, above 90% of the children have some degree of dental fluorosis. The main source of exposure to fluoride is tap water. The objective of the study was to evaluate the
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Fluoride and arsenic exposure affects spatial memory and activates the ERK/CREB signaling pathway in offspring rats
Highlights Fluoride and arsenic exposure decrease the ability of learning and memory. Found changes in the level of protein expression about ERK/CREB on rat pups. It was found that the potential synergetic effect of fluoride and arsenic. Fluoride and arsenic are inorganic contaminants that occur in the natural environment. Chronic fluoride
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Fluoride-Induced Damage to Gastric Mucosa in Human Clinical Trials
When fluoride has been used (at doses of 18-34 mg/day) as an experimental treatment for osteoporosis, gastric pain is one of the two main side effects consistently encountered. To better understand how fluoride causes this effect, researchers have sought to determine how fluoride affects the tissue that lines the gastrointestinal tract. In a
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Side Effects from Fluoride Gels: Gastric Distress
Gastric distress -- including nausea, pain, and vomiting -- is one the most common side effects from professional application of "fluoride gels" at the dentist. Patients receiving fluoride gels can swallow more than 20 mg of fluoride from a single treatment -- doses that far exceed the doses that can
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Gastrointestinal Problems Among Individuals with Skeletal Fluorosis
Humans suffering from skeletal fluorosis are known to suffer from an increased occurrence of gastrointestinal disorders. When fluoride intake is reduced, these gastrointestinal problems are among the first symptoms to disappear. The following are some of the studies that have examined this issue: "It is clear from the observations presented in this article
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Fluoride & Gastrointestinal System: The Importance of Fluoride Concentration in Stomach
The following is an excerpt from the National Research Council's (2006) review of fluoride toxicity: "It is important to realize that GI effects depend more on the net concentration of the aqueous solution of fluoride in the stomach than on the total fluoride dose in the fluid or solid ingested. The
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Fluoride-Induced Gastric Symptoms in Human Clinical Trials
In studies where fluoride has been used (at doses of 18-34 mg/day) as an experimental drug for the treatment of osteoporosis, gastrointestinal disturbances are one of the two main side effects consistently encountered. The following are some of the accounts from the published literature: "The use of fluoride in the prophylaxis or
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