The oestrone loading test was carried out on fifteen patients suffering from fluorine liver damage. Three pattern curves of the oestrogen fraction (oestrone, 17?-oestradiol and oestriol) excretion in the urine were established. Our data show that there were disturbances in oestrogen metabolism in patients with fluorine liver damage.
In vivo protective effects of quercetin against sodium fluoride-induced oxidative stress in the hepatic tissue
The protective effects of quercetin against sodium fluoride induced oxidative stress were examined in rat’s liver. Rats were divided into five groups. The first group served as normal group that was treated with standard diet. The second group was intoxicated with sodium fluoride (600 ppm) through drinking water for 1 week. The
Gluconeogenesis and glycogenolysis in fluoride-treated rats.
Intraperitonial administration of 10 mg fluoride (NaF)/kg body weight resulted in hyperglycemia in rats. Role of gluconeogenesis and glycogenolysis in this hyperglycemic response was evaluated. Results of the study indicate that the fluoride induced hyperglycemia is mainly due to increased hepatic glycogenolysis.
Study on blood biochemical diagnostic indices for hepatic function biomarkers in endemic skeletal fluorosis
The aim of the study was to determine the relationship of fluoride in drinking water to liver function in individuals living in normal and seven endemic fluorosis areas of Punjab, India. The concentration of fluoride in drinking water of different areas varied from 5.9 to 24.5 mg/L. Study group consisted
The effects of the inhalation of hydrogen fluoride. II. The response following exposure to low concentration.
The effects of the inhalation of hydrogen-fluoride (7664-39-3) (HF) on several animals was investigated. Five rabbits, three guinea-pigs and two Rhesus-monkeys were exposed to atmospheric HF at a concentration of 0.0152 milligrams per liter for 6 hours a day. This was repeated for 30 days until a total of 309
Studies on the toxicology of fluorine compounds. I. Histological and histochemical investigations on the liver, heart, lungs, and stomach of rats exposed to hydrogen fluoride
The liver, heart, lungs, and stomach of rats exposed to hydrogen fluoride were studied. Histological examination showed partial liver necrosis and emphysema. Using histochemical methods the effect of fluorine ions was found in: a reduction of the activity of succinic and beta-hydroxybutyric dehydrogenases in the liver, heart muscle, superficial and
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