Abstract
Fluorosis of coal burning is a new type of endemic fluorosis in China, which affects the male reproductive system. Furthermore, the content of fluoride in the semen, sperm mortality, sperm concentration and the incidence of infertility are higher in severe fluorosis areas than in mild- and non-fluorosis areas, so are the levels of serum follicle-stimulating hormone and luteinizing hormone. However, the levels of inhibin B, serum testosterone and estradiol show different degrees of reduction in severe fluorosis areas. Accordingly, fluorosis of coal burning, just like other endemic fluorosis, may affect the structure of male reproductive organs, the generation of sperm and reproductive endocrinology, resulting in the decline of men’s reproductive ability.
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NaF may disturb male fertility in rodents
An increase in the potential for lipoperoxidation in the rat testis and a decrease in rodents fertility by NaF has been reported (Pinto et al., 1997, Pharm. Toxicol., 80, III, 117; Chinoy et al., 1992, J. Environ. Biol 13, 55). However, other authors described that spermatogenesis in the rat is
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Effects of fluoride and aluminum on expressions of StAR and P450scc of related steroidogenesis in guinea pigs' testis
Highlights F and Al changed histological structure of testes, reduced sperm quality. F and Al reduced StAR and P450scc expressions and level of serum testosterone. F toxicity is stronger than Al and Al weakened the toxicity of F. Al had antagonism effects on F. A lot of studies have shown
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Evaluation of vitamin E and calcium effects on fluoride toxicity-induced fertility impairment
Chronic fluoride (Fl) toxicity is a serious public health problem globally where drinking water contains more than 1 ppm of Fl. Sodium fluoride (NaF) produced male reproductive system toxicity. The aim of the present study was to evaluate the amelioration of Fl toxicity-induced fertility impairment by vitamin E and calcium
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Suppression of male reproduction in rats after exposure to sodium fluoride during early stages of development
Sodium fluoride (NaF), a widespread natural pollutant was given to sperm-positive female rats throughout gestation and lactation at a dose of 4.5 and 9.0 ppm via drinking water. The neonates were allowed to grow up to 90 days on tap water, and then sperm parameters, testicular steroidogenic marker enzyme activity
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Effect of high fluoride on the reproductive performance of the male rat
The effect of high fluoride intake (100 and 200 ppm) in the ration was studied in male rats. After sixty days of treatment, rats showed a decrease in the mean diameter of the seminiferous tubules and the percentage of the tubules containing spermatozoa and an increase in the thickness of
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Fluoride's Effect on Male Reproductive System - Human Studies
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Fluoride's Effect on Male Reproductive System: Animal Studies
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Fluoride's Effect on the Male Reproductive System -- In Vitro Studies
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Fluoride's Effect on Male Reproductive System -- The "Sprando/Collins" Anomaly
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