Abstract
Objective: Explore the effect of different doses of chronic exposure of fluoride on rat learning and memory behavior. Method: Selected 46 Wistar rats, randomly divided them into a control group, low-fluoride group, and high-fluoride group, had them respectively drink tap water (control group), 100 mg/L (low-fluoride group), and 200 mg/L (high-fluoride group) sodium fluoride solutions, then five months later used a Y-maze test to observe the effect of chronic fluorosis on the learning and memory behavior of the rats. Results: Compared to the number of times required for the control group to learn the Y-maze test (58.83 +/- 25.12), there was a significant increase (P<0.05) in the number of times required by the low-fluoride group (73.95 +/- 9.77) and high-fluoride group (77.37 +/- 8.69) to learn it, and although the number of times required to learn it increased with the fluoride exposure dose, it was not statistically significant (P>0.05). Conclusion: The results indicate that chronic fluorosis has a significant effect on rat learning and memory behavior.
(Translated by Alta Language Services in February 2014, courtesy of Fluoride Action Network)
-
-
Components of Drinking Water and Risk of Cognitive Impairment in the Elderly.
The relation between aluminum, fluorine, calcium, and pH in drinking water and the risk for cognitive impairment was studied using data collected in 1988-1989 in a population-based survey of 3,777 French men and women aged 65 years and older (the Paquid study). Cognitive impairment was defined as a score lower
-
Fluoride exposure during pregnancy from a community water supply is associated with executive function in preschool children: A prospective ecological cohort study
Highlights Maternal fluoride exposure from drinking water was associated with executive function. Poorer inhibitory control and cognitive flexibility were found, particularly in girls. Maternal fluoride exposure was not associated with lower intelligence in children. Water fluoridated at the recommended level of 0.7 mg/L may adversely affect executive function. Background On May 19,
-
Research on the neurobehavioural function of workers occupationally exposed to fluoride.
Sixty-five operations workers (all males) in an electrolytic aluminum production facility were divided into two groups. The first group of 37 was employed for more than 5 years, and the second group of 28 for 5 years or less. These men had no history of liver, kidney, or immune-related disease. X-ray tests indicated that they were not suffering
-
Protective effect of ascorbic acid and Ginkgo biloba against learning and memory deficits caused by fluoride.
Fluoride is present in the ground water, World Health Organization permitted level of fluoride in the ground water is 0.5 ppm. Tooth pastes, mouth washes, tea and sea fish are the sources of fluoride. Exposure to these multiple sources results in several adverse effects in addition to the fluorosis. The
-
Chronic aluminum fluoride administration. I. Behavioral observations
This study examined the behavioral effects of chronic ingestion of various monofluoroaluminum complexes (AlF3) in drinking water. Forty young adult male Long-Evans rats were divided into four groups of 10 rats each. The groups received different concentrations of AlF3 in the drinking water from three sample solutions having a total
Related Studies :
-
-
-
Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
-
Fluoride Affects Learning & Memory in Animals
An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out
-
Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
-
Fluoride & IQ: 76 Studies
Note: See the Updated list of fluoride IQ studies at https://fluoridealert.org/researchers/fluoride-iq-studies/the-fluoride-iq-studies/ • As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies
-
NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
The NRC's analysis on fluoride and the brain.
Related FAN Content :
-