Abstract

[Objective] To investigate the effect of iodine and selenium on learning memory behavior impairment induced by fluorosis and blood biochemical criterion change of rats. To study the antagonism of iodine and selenium on fluorosis. [Methods] After the rats with fluorosis drinking water with different concentrations of iodine ( I) and selenium ( Se) for a long time, their learning memory abilities were measured by way of Y- maze, and the blood biochemical criterions were determined at the same time. [Results] The learning memory abilities of rats in high F group, high I/high F group, and low I/high F group were significantly lower than control group, while the learning memory abilities of rats given proper concentration I and Se increased significantly. The blood biochemical criterions of high F group, high I/high F group, and low I/high F group presented marked differences from that of groups given proper concentration I and Se. [Conclusion] Proper concentration I and Se have obvious antagonism against rat fluorosis. The antagonism may be related with the changes of blood biochemical criterion.

• Related Studies :

  • The relationships between thyroid-stimulating hormone and/or dopamine levels in peripheral blood and IQ in children with different urinary iodine concentrations.

    Highlights TSH is not related IQ in children with different urinary iodine concentrations. Dopamine in plasma is unrelated to IQ in children with adequate or excessive iodine. Dopamine has positive correlation with intelligence in iodine deficiency group. The interaction between dopamine in plasma and TSH is not related to

  • Research on the effects of fluoride on child intellectual development under different environments

    Goal:  To study the effects of the fluoride and iodine content of drinking water on child intellectual development and the interaction between the two factors and also the relationship of educational factors to such development. Methods: The subjects of the investigation were 8- to 14-year-old children randomly selected from endemic areas as well

  • [Effects of high fluoride and low Iodine on learning-memory and TchE of brain in offspring rats].

    Objective To study the effect of high level fluoride and low level iodine on learning-memory in offspring rats and possible mechanism. Methods Thirty-two Wistar rats were randomly divided into four groups each of eight (female:male=(3:1).) The rats were treated with high fluoride (100 and 150 mg NaF/L), low iodine (0.0855 mg/kg),

  • Effects of high iodine and high fluorine on children’s intelligence and thyroid function.

    Objective: Try to find out the effects of high iodine and high fluorine on children’s intelligence and thyroid function. Methods: We selected in Qingyun County the Lidian Primary School, where the iodine and fluorine in the water are relatively high in concentration as the investigative point and Dading Primary School where the iodine and

  • Fluoride-induced developmental disorders and iodine deficiency disorders as examples of developmental disorders due to disturbed thyroid hormone metabolism.

    Both exposure to fluoride and iodine deficiency during early development can lead to disturbed thyroid hormone metabolism and produce the same spectrum of developmental disorders including short stature, bone deformities, cognitive impairment, delayed dental eruption, and dental fluorosis. The levels of creatinine-adjusted urinary fluoride experienced by pregnant women in areas

• Related FAN Content :

  • Fluoride Exposure Increases Metabolic Requirement for Calcium & Vitamin D

    It is well known that individuals with nutrient deficiencies are more susceptible to fluoride toxicity, including fluoride's bone effects. As discussed in the following studies, fluoride increases the skeleton's need for calcium (and vitamin D) by increasing the amount of unmineralized tissue (osteoid) in the bone. When insufficient calcium and

  • Fluoride & IQ: 67 Studies

    As of May 2020, a total of 75 studies have investigated the relationship between fluoride and human intelligence. Of these investigations, 67 studies have found that elevated fluoride exposure is associated with reduced IQ in humans, while over 60 animal studies have found that fluoride exposure impairs the learning and/or

  • NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects

    The NRC's analysis on fluoride and the brain.

  • Fluoride: Developmental Neurotoxicity.

    Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching

  • The Relationship Between Fluoride Exposure & Goitre in South Africa

    As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.