Abstract

A case report of a Caucasian female born in 1927 is presented in which rapid recovery from vulvar extramammary Paget’s disease (EMPD) without surgical intervention occurred following an abrupt change from fluoridated/chlorinated tap water (0.9- 1.0 mg F–/L) to low-fluoride spring and well water (both <0.1 mg F–/L) for drinking, cooking, bathing, and laundry purposes. Within weeks of switching from the tap water her condition completely cleared, with no recurrence after three years except when re-exposed to fluoridated tap water. EMPD primarily affects postmenopausal Caucasian women, but occasionally it also occurs in men. The condition presents as an itchy, rash-like condition that can be accompanied by invasive malignant changes to underlying dermal tissue, for which surgical excision of the affected region is the most common treatment. Possible reasons for recovery without surgery in this case are discussed.

• Related Studies :

  • Allergy and hypersensitivity to fluoride

    A review of the literature was undertaken in response to four recent reviews which found that the evidence that fluoride was an allergen was unconvincing. Reports were found of urticaria, contact dermatitis and stomatitis occurring in response to fluoride, settling on the withdrawal of fluoride and recurring with appropriate challenges.

  • Prenatal and postnatal ingestion of fluorides: fourteen years of investigation -- final report*.

    SUMMARY Data is presented showing that fluoride ingested by gravid women enters the maternal circulation, is stored in the placenta and passes through the placental barrier to enter the foetal blood supply. Evidence is presented that the fluoride in the foetal blood supply affects the developing teeth to make them more resistant

  • Contact dermatitis and stomatitis due to amine fluoride

    Case Report For prevention of dental caries, a 17-year-old boy had intermittently used a gel containing different fluoride compounds over a period of 2 years. In the last 2 months, 1 to 2 days after application, he had developed itchy perioral erythematous papules and plaques, with vesicles of the oral mucosa.

  • Allergy to fluoride

    Six children and one adult exhibited various allergic reactions after the use of toothpaste and vitamin preparations containing fluoride. The following conditions were encountered: Urticaria, exfoliative dermatitis, atopic dermatitis, stomatitis, gastro-intestinal and respiratory allergy.

  • Perioral dermatitis from high fluoride dentifrice: a case report and review of literature

    Perioral dermatitis is a papulopustular eruption, commonly related to the inappropriate application of topical corticosteroids with occasional reports of inhaled corticosteroids and decreased personal hygiene. We present a case of a 45-year-old female with a one-year history of perioral dermatitis related to the use of highly fluoridated toothpaste commenced to

• Related FAN Content :

  • Physician's Desk Reference: Fluoride Hypersensitivity

    The following are excerpts from various editions of the Physicians' Desk Reference (PDR). "In hypersensitive individuals, fluorides occasionally cause skin eruptions such as atopic dermatitis, eczema or urticaria. Gastric distress, headache and weakness have also been reported. These hypersensitivity reactions usually disappear promptly after discontinuation of the fluoride. In rare cases,

  • Fluoride-Enhanced Inflammation of Skin in Animals:

    The possibility that topical fluorides can provoke inflammtory skin disorders gains is supported by carefully controlled studies on animals. When topical fluoride has been applied to the skin of rabbits or rats, inflammation has been repeatedly noted when the skin is cut or damaged prior to the application. Studies Examining Fluoride-Induced Inflammation of Skin in

  • Unheeded Warnings: Government Health Authorities Ignore Fluoride Risk for Kidney Patients

    Despite the well known fact that individuals with kidney disease are at much higher risk of fluoride toxicity than the general population, there has yet to be any attempt in the United States, or any other country that practices mass-scale water fluoridation to determine the prevalence of fluoride-related effects (e.g.,

  • Case Reports of Hypersensitivity to Ingested Fluorides

    In the 1950s, the renowned allergist George Waldbott discovered that some individuals are hypersensitive to ingested fluoride. In a series of case reports and double-blind studies, Waldbott and other doctors found relatively small doses of ingested fluoride, including the consumption of fluoridated water, could induce side effects that would quickly

  • Is the Ingestion of Fluoride an Immunosuppressive Practice?

    This paper records several observations which suggest that habitual ingestion of small doses of fluoride, even as small as the 1 mg/L contained in fluoridated water, may decrease the function of the immune system.