Abstract

A case report of a Caucasian female born in 1927 is presented in which rapid recovery from vulvar extramammary Paget’s disease (EMPD) without surgical intervention occurred following an abrupt change from fluoridated/chlorinated tap water (0.9- 1.0 mg F–/L) to low-fluoride spring and well water (both <0.1 mg F–/L) for drinking, cooking, bathing, and laundry purposes. Within weeks of switching from the tap water her condition completely cleared, with no recurrence after three years except when re-exposed to fluoridated tap water. EMPD primarily affects postmenopausal Caucasian women, but occasionally it also occurs in men. The condition presents as an itchy, rash-like condition that can be accompanied by invasive malignant changes to underlying dermal tissue, for which surgical excision of the affected region is the most common treatment. Possible reasons for recovery without surgery in this case are discussed.

• Related Studies :

  • Prenatal and postnatal ingestion of fluorides: fourteen years of investigation -- final report

    Three different sources of fluoride were used in this study. The tablets containing 1.0 mgm fluorine ion from CaF2; 1.2 mgm fluorine ion, from NaF and 0.825 mgm fluorine ion from Na2PO3F, each. These values were chosen so that each tablet would contain approximately the same amount of the ion

  • Contact dermatitis and stomatitis due to amine fluoride

    Case Report For prevention of dental caries, a 17-year-old boy had intermittently used a gel containing different fluoride compounds over a period of 2 years. In the last 2 months, 1 to 2 days after application, he had developed itchy perioral erythematous papules and plaques, with vesicles of the oral mucosa.

  • Allergy to fluoride

    Six children and one adult exhibited various allergic reactions after the use of toothpaste and vitamin preparations containing fluoride. The following conditions were encountered: Urticaria, exfoliative dermatitis, atopic dermatitis, stomatitis, gastro-intestinal and respiratory allergy.

  • Prenatal and postnatal ingestion of fluoride salts: a progress report.

    Undesirable Effects Out of the 601 cases in the adult group, six have shown undesirable side effects from the fluoride supplement. Five out of the 495 children have presented evidence of undesirable reactions. This is 1 per cent incidence of side effects. Reactions in Adults - Included in the adult cases are

  • Allergy in horses from artificially fluoridated water

    As described recently in Fluoride, horses on artificially fluoridated water (AFW) developed chronic fluoride poisoning. This report describes an allergic manifestation as an addition to the classical signs of fluorosis, viz., urticaria. The skin lesions disappeared promptly when an affected horse was removed from AFW and returned promptly when the

• Related FAN Content :

  • Fluoridation, Dialysis & Osteomalacia

    In the 1960s and 1970s, doctors discovered that patients receiving kidney dialysis were accumulating very high levels of fluoride in their bones and blood, and that this exposure was associated with severe forms of osteomalacia, a bone-softening disease that leads to weak bones and often excruciating bone pain. Based on

  • Dental Fluorosis & Enamel Hypoplasia in Children with Kidney Disease

    Children with kidney disease are known to have high levels of fluoride in their blood and to be at risk for disfiguring tooth defects. Research suggests that high levels of fluoride in blood, which can cause the tooth defect known as dental fluorosis, can contribute to the defects that occur

  • Kidney Patients Are at Increased Risk of Fluoride Poisoning

    It is well established that individuals with kidney disease are susceptible to suffering bone damage and other ill effects from low levels of fluoride exposure. Kidney patients are at elevated risk because when kidneys are damaged they are unable to efficiently excrete fluoride from the body. As a result, kidney patients

  • Prenatal and postnatal ingestion of fluorides - A progress report.

    The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.

  • Fluoride & Perioral Dermatitis

    Perioral dermatitis (PD) is a common rosacea-like dermatitis that was never reported prior to the mid-fifties. Although it can affect both sexes and all ages, most patients are women ages 20-50 years. Patients with PD frequently report a pre-existing tendency to blush. This disease is most likely multifactorial in origin, and fluoride preparations in dentrifices probably have played a role as precipitator.