Abstract

A review of the literature was undertaken in response to four recent reviews which found that the evidence that fluoride was an allergen was unconvincing. Reports were found of urticaria, contact dermatitis and stomatitis occurring in response to fluoride, settling on the withdrawal of fluoride and recurring with appropriate challenges. It is concluded that the four reviews were seriously incomplete in their coverage of the literature, and that when a more complete examination is made there are reasonable grounds for concluding that there are individuals in whom allergy or hypersensitivity to fluoride has been demonstrated. The sources of fluoride included those used in the fluoridation of community water supplies.

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