Abstract
OBJECTIVE: To study the effects caused by uptake of different levels of calcium to dental fluorosis in rats.
METHODS: Weanling rats were raised on water containing 0.1 mol/L fluoride and food containing low, normal and high levels of calcium for 2 months. The concentration of fluoride in enamel was analysed by F-ion-selective electrode. The microradiographic examination and light-density analysis were performed. The enamel structure was examined under SEM.
RESULTS: The more calcium was ingested, the lower level of fluoride amount in enamel was observed (P < 0.01). With increasing food calcium ingestion, the light density value was decreasing, and the level of enamel mineralization was increasing (P < 0.01).
CONCLUSIONS: With increasing food calcium ingestion during the development of teeth, the level of dental fluorosis is decreasing. The calcium supply is effective in protection from fluoride toxicity to a certain extent.
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Epidemiological, clinical, and biochemical study of endemic dental and skeletal fluorosis in Punjab
The incidence of dental fluorosis in 46,000 children in the Punjab was assessed and compared with the fluoride content of their water supplies. Ten villages were selected for more detailed studies of skeletal as well as dental fluorosis. Factors other than the fluoride content of the drinking water which were found to influence
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Nutrition survey in dental fluorosis-afflicted areas
The fluoride (F) intake, diet, and health status of children in two dental fluorosis-afflicted areas in the Province of Jiangxi, China were studied in an attempt to correlate nutritional status with dental fluorosis. The relationship between mild consumption and the incidence of dental fluorosis among children was stressed in this
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Environmental and physiological factors affecting dental fluorosis
In addition to differences in fluoride intake and possibly to calcium deficiency or malnutrition, there are several factors which may account for individual differences in the occurrence of dental fluorosis. Disorders in acid-base balance affect the renal handling of fluoride such that, in acidosis, the excretion rate is diminished and,
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Relation of endemic dental fluorosis to malnutrition
Summary The prevalence and severity of endemic dental fluorosis were studied in 928 undernourished inhabitants who had resided since birth in two fluoride endemic areas in Italy (Compagnano di Roma and Quarto). The data were compared with the index of mottling in endemic areas in the United States with similar fluorine
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Association of dental and skeletal fluorosis with calcium intake and vitamin D concentrations in adolescents from a region endemic for fluorosis
Objective: Patan, is a semi urban area in Gujarat, India where fluorosis is endemic (Fluoride concentration in ground water 1.96–10.85 ppm, Patel et al., 2008). Exposure to fluoride is likely to be higher in lower socio-economic class (SEC) due to lack of access to bottled water. Calcium intake and vitamin
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Nutrient Deficiencies Enhance Fluoride Toxicity
It has been known since the 1930s that poor nutrition enhances the toxicity of fluoride. As discussed below, nutrient deficiencies have been specifically linked to increased susceptibility to fluoride-induced tooth damage (dental fluorosis), bone damage (osteomalacia), neurotoxicity (reduced intelligence), and mutagenicity. The nutrients of primary importance appear to be calcium,
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Racial Disparities in Dental Fluorosis
In 2005, the Centers for Disease Control published the results of a national survey of dental fluorosis conducted between 1999 and 2002. According to the CDC, black children in the United States have significantly higher rates of dental fluorosis than either white or Hispanic children. This was not the first time that black children were found to suffer higher rates of dental fluorosis. At least five other studies -- dating as far back as the 1960s -- have found black children in the United States are disproportionately impacted by dental fluorosis.
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Dental Fluorosis Is a "Hypo-mineralization" of Enamel
Teeth with fluorosis have an increase in porosity in the subsurface enamel ("hypomineralization"). The increased porosity of enamel found in fluorosis is a result of a fluoride-induced impairment in the clearance of proteins (amelogenins) from the developing teeth. Despite over 50 years of research, the exact mechanism by which fluoride impairs amelogin
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Severe Dental Fluorosis: Perception and Psychological Impact
[caption id="attachment_8879" align="aligncenter" width="550"] Severe fluorosis - Photograph by David Kennedy, DDS[/caption] In its severe forms, dental fluorosis causes highly disfiguring brown and black staining of the teeth, which can cause chronic embarrassment and social anxiety for the impacted child. In 1984, a panel from the National Institute of Mental Health (NIMH) warned
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Community Fluorosis Index (CFI)
The current Community Fluorosis Index for U.S. adolescents as a whole (from both fluoridated and non-fluoridated areas) is roughly 5 times higher than the CFI health authorities predicted for fluoridated areas when fluoridation first began. It is also higher than the CFI that the NIDR found in fluoridated areas back in the 1980s. It is readily apparent, therefore, that children are ingesting far more fluoride than was the case in the 1950s, and even as recently as the 1980s.
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