Abstract
Data based on a total number of 1,387,027 births were used to compare the incidence of selected congenital malformations in fluoridated areas and that in areas where the water supply is deficient in fluoride.
The incidence of selected congenital malformations in areas with fluoride supplementation of public water supplies was compared with the incidence in areas where the water supply is deficient in fluoride. Comparison of the incidences of several common birth defects (including Down’s syndrome) in fluoridated and nonfluoridated areas revealed no substantial or significant differences in which there was a consistent pattern for both sets of data.
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Fluoride-linked down syndrome births and their estimated occurrence due to water fluoridation
Down syndrome (DS) birth rates (BR) as a function of maternal age exhibit a relatively flat linear regression line for younger mothers and a fairly steep one for older mothers with the second line intersecting the first line a little above maternal age 30. Consequently, overall DS-BR for all maternal
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Down syndrome, water fluoridation, and maternal age
It has been claimed that there is a positive association between the frequency of Down syndrome and the fluoridation of drinking water. It has also been suggested that this association is most pronounced in young women. Recent congenital malformations data obtained from birth certificates from large U.S. cities have been
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[New researches on mongolism related to the disease producing role of fluorine].
A new statistical study on the distribution of mongolism in cities in Illinois, United States, from January 1, 1950 to December 31, 1956, permits us to verify an increasing frequency of this affliction associated with the concentration of fluorine in the drinking water. This study follows a preceding inquiry on the
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Role des inhibiteurs enzymatiques dans l'etiologie du mongolisme
1) The low incidence of dental caries observed in mongoloid patients led to an investigation of the role of fluorine in this condition. 2) A statistical study of the geographical distribution of mongolism in Wisconsin, Illinois, Idaho, North and South Dakota (U.S.A.) shows a parallelism between the prevalence of this condition
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Fluoridation and the occurrence of Down's syndrome
The prevalence rates of Down's syndrome at birth were compared for Massachusetts residents ingesting fluoridated and non-fluoridated water. The observations included nearly all children born alive with Down's syndrome in Massachusetts during the 17-year period 1950-1966. A rate of 1.5 cases per 1000 births was found for fluoride-related births and
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