Abstract

1) The low incidence of dental caries observed in mongoloid patients led to an investigation of the role of fluorine in this condition.

2) A statistical study of the geographical distribution of mongolism in Wisconsin, Illinois, Idaho, North and South Dakota (U.S.A.) shows a parallelism between the prevalence of this condition and the amount of fluoride in the water supply.

3) A new hypothesis on the pathogenesis of mongolism is proposed: the blockage of an enzymatic system by an inhibitor, such as fluorine, at an early stage of the fetal development.

• Related Studies :

  • [New researches on mongolism related to the disease producing role of fluorine].

    A new statistical study on the distribution of mongolism in cities in Illinois, United States, from January 1, 1950 to December 31, 1956, permits us to verify an increasing frequency of this affliction associated with the concentration of fluorine in the drinking water. This study follows a preceding inquiry on the

  • Oligophrenie mongolienee et caries dentaires

    Une enquête épidémiologique sur la fréquence du mongolisme dans quelques Etats du Midwest américain nous a permis de mettre en évidence les faits suivants: 1: un parallélisme entre la fréquence du mongolisme et la teneur en fluor de l'eau de boisson; 2: une rareté relative des caries dentaires chez les mongoliens; 3: une

  • Editorial review: Fluoride and down's syndrome (mongolism)

  • Toxicity assessment of sodium fluoride in Drosophila melanogaster after chronic sub-lethal exposure

    Sodium fluoride (NaF), one of the most frequently used fluoride compound is composed of Na+ and F-. Apart from its use in water fluoridation, NaF also acts as a major component for different dental products like toothpastes, gels and mouth rinses etc. The present study was carried out to explore the toxic impact of chronic

  • Association of Down's syndrome and water fluoride level: a systematic review of the evidence

    Background: A review of the safety and efficacy of drinking water fluoridation was commissioned by the UK Department of Health to investigate whether the evidence supported a beneficial effect of water fluoridation and whether there was any evidence of adverse effects. Down's syndrome was one of the adverse effects reported. The

• Related FAN Content :

  • Fluoride's Effect on Fetal Brain

    The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts