Abstract

The aim of this study was to evaluate the effects of fluoride on anxiety and depression in mice. Control and study groups were formed with ten 4-month-old male Swiss mice in each group. For 90 days, mice in the control group were given drinking water containing 0.3 ppm fluoride while the study group was given water with 40 ppm fluoride. Tail suspension was not significantly different between the study and the control groups. In an open field test, however, the number of defecations was higher in the study group, and transitions, rearing, and grooming activities were less frequent. Under these conditions, fluoride appeared to have no antidepressant effect in mice but rather an anxiety stimulating effect.

• Related Studies :

  • Human epiphyseal concrements in schizophrenia.

    The epiphysis is a gland containing firm extracellular bodies (brain sand) the number of which increases with age. Microscopy and roentgen microtomography showed that in some cases of schizophrenia the amount of brain sand decreases. In parallel, cytoplasm of pinealocytes appears to contain concrements of a new type--irregular hollow spheres

  • Research on the neurobehavioural function of workers occupationally exposed to fluoride.

    Sixty-five operations workers (all males) in an electrolytic aluminum production facility were divided into two groups. The first group of 37 was employed for more than 5 years, and the second group of 28 for 5 years or less. These men had no history of liver, kidney, or immune-related disease. X-ray tests indicated that they were not suffering

  • Components of Drinking Water and Risk of Cognitive Impairment in the Elderly.

    The relation between aluminum, fluorine, calcium, and pH in drinking water and the risk for cognitive impairment was studied using data collected in 1988-1989 in a population-based survey of 3,777 French men and women aged 65 years and older (the Paquid study). Cognitive impairment was defined as a score lower

  • Developmental toxicity of sodium fluoride in rats.

    Despite the chronic exposure of the US population to fluoridated drinking water since the 1940s, existing studies have been judged inadequate to determine any potential reproductive or developmental hazard. This study was conducted to determine the effects of sodium fluoride (NaF) on foetal development. Sperm-positive female rats were given 0,

  • Effect of NaF on albino female mice with special reference to behavioral studies and ACh and AChE levels

    The present study investigates the effect of the Sodium Fluoride (NaF) on Wistar Albino mice. The animals have been divided into three batches each containing five individuals among which 1 batch served as control while, remaining two batches were treated with 5 and 10ppm respectively. After completion of exposure, the

• Related FAN Content :

  • Fluoride's Direct Effects on Brain: Animal Studies

    The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.

  • Fluoride & IQ: 69 Studies

    As of June 2021, a total of 77 studies have investigated the relationship between fluoride and human intelligence. Of these investigations, 69 studies have found that elevated fluoride exposure is associated with reduced IQ in humans, while over 60 animal studies have found that fluoride exposure impairs the learning and/or

  • Fluoride Affects Learning & Memory in Animals

    An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out

  • Fluoride's Effect on Fetal Brain

    The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts

  • Fluoride: Developmental Neurotoxicity.

    Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching