Abstract

The Intelligence Quotient (IQ) was measured in 118 children, aged 10-12 years, who were life-long residents in two villages of similar population size and social, educational and economic background but differing in the level of fluoride in drinking water. The children in the high-fluoride area (drinking water fluoride 3.15 ± 0.61 mg/L [ppm]) (mean ± S.D.) had higher urinary fluoride levels (4.99 ± 2.57 mg/L) than the children in the low-fluoride area (drinking water fluoride 0.37 ± 0.04 mg/L) (urinary fluoride 1.43 ± 0.64 mg/L). The IQ of the 60 children in the high-fluoride area was significantly lower, mean 92.27 ± 20.45, than that of the 58 children in the low-fluoride area, mean 103.05 ± 13.86. More children in the high-fluoride area, 21.6%, were in the retardation (<70) or borderline (70-79) categories of IQ than children in the low fluoride area, 3.4%. An inverse relationship was also present between IQ and the urinary fluoride level. Exposure of children to high levels of fluoride may therefore carry the risk of impaired development of intelligence.

• Related Studies :

  • Association Between Water Fluoride and the Level of Children's Intelligence: A Dose-Response Meta-Analysis.

    Highlights High fluoride content in drinking water could affect the intellectual development of children. High water fluoride exposure is significantly associated with a reduced level of intelligence. Water quality and water fluoride exposure should be improved in areas with high water fluoride content. Objectives Higher fluoride concentrations in water have inconsistently

  • Dopamine receptor D2 gene polymorphism, urine fluoride, and intelligence impairment of children in China: A school-based cross-sectional study.

    Highlights Urine fluoride was inversely associated with IQ. DRD2 Taq 1A polymorphism was not related to IQ in children exposed to high fluoride. Urine fluoride had a stronger association with IQ in children with TT genotype. The threshold of urine fluoride affecting IQ in children with TT genotype existed. Objective:

  • Developmental fluoride neurotoxicity: an updated review.

    Background After the discovery of fluoride as a caries-preventing agent in the mid-twentieth century, fluoridation of community water has become a widespread intervention, sometimes hailed as a mainstay of modern public health. However, this practice results in elevated fluoride intake and has become controversial for two reasons. First, topical fluoride application

  • The effects of high fluoride on the level of intelligence of primary and secondary students.

    The harm of long-term intake of excessive fluoride on the human skeletal system has been proved. There are also reports about the effects of high fluoride on the human nervous system and mental development [1, 2]. Some studies have proved that if the mother has taken in an excessively high amount of fluoride, she can

  • Dental fluorosis and urinary fluoride concentration as a reflection of fluoride exposure and its impact on IQ level and BMI of children of Laxmisagar, Simlapal Block of Bankura District, W.B., India

    There has been growing public concern about intellectual performance of children at high levels of fluoride exposure. A cross-sectional study was conducted in Simlapal Block of Bankura District, West Bengal, to find out the relationship between fluoride (F) exposure as exposure dose (ED) with dental fluorosis (DF), urinary fluoride concentration

• Related FAN Content :

  • Fluoride & IQ: 76 Studies

    • As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies which reported an association of reduced IQ with exposure

  • Fluoride Affects Learning & Memory in Animals

    An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out

  • NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects

    The NRC's analysis on fluoride and the brain.

  • Fluoride's Direct Effects on Brain: Animal Studies

    The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.

  • Fluoride: Developmental Neurotoxicity.

    Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching