Abstract
OBJECTIVE: Prolonged excessive intake of fluoride during child’s growth and development stages has been associated with mental and physical problems. The aim of this study was to investigate the effect of excessive fluoride intake on the intelligence quotient (IQ) of children living in five rural areas in Makoo/Iran.
MATERIALS AND METHODS: In this cross-sectional study, 293 children aged 6-11 years were selected from five villages in Makoo with normal fluoride (0.8±0.3 ppm), medium fluoride (3.1±0.9 ppm) and high fluoride (5.2±1.1 ppm) in their water supplies. The IQ of each child was measured by the Raven’s test. Educational and residential information and the medical history of each child was recorded by a questionnaire completed by the parents. Data were analyzed by ANOVA test with a significance level of 0.05.
RESULTS: The mean IQ scores decreased from 97.77±18.91 for the normal fluoride group to 89.03±12.99 for the medium fluoride group and to 88.58±16.01 for the high fluoride group (P=0.001).
CONCLUSION: Children residing in areas with higher than normal water fluoride levels demonstrated more impaired development of intelligence. Thus, children’s intelligence may be affected by high water fluoride levels.
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Developmental neurotoxicity of fluoride: a quantitative risk analysis toward establishing a safe daily dose of fluoride for children
Background: A recent 2015 study from New Zealand indicated water fluoridation did not have an effect on children’s IQs. A 2012 meta-analysis showed that children with higher fluoride exposure have lower IQs than similar children with lower exposures. Levels of the fluoride ion (F) in blood and urine in children
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Critical Windows of Fluoride Neurotoxicity in Canadian Children.
Highlights The association between fluoride and performance IQ (PIQ) significantly differed across prenatal, infancy, and childhood exposure windows collapsing across child sex (p = .001). The strongest association between fluoride and PIQ was during the prenatal window, B = -2.36, 95% CI: -3.63, -1.08; the association was also significant
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Dental fluorosis and urinary fluoride concentration as a reflection of fluoride exposure and its impact on IQ level and BMI of children of Laxmisagar, Simlapal Block of Bankura District, W.B., India
There has been growing public concern about intellectual performance of children at high levels of fluoride exposure. A cross-sectional study was conducted in Simlapal Block of Bankura District, West Bengal, to find out the relationship between fluoride (F) exposure as exposure dose (ED) with dental fluorosis (DF), urinary fluoride concentration
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The effects of high fluoride on the level of intelligence of primary and secondary students.
The harm of long-term intake of excessive fluoride on the human skeletal system has been proved. There are also reports about the effects of high fluoride on the human nervous system and mental development [1, 2]. Some studies have proved that if the mother has taken in an excessively high amount of fluoride, she can
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Effect of fluoride in drinking water on dental caries and IQ in children.
The aim of this work was to evaluate the impact of fluoride exposure on the prevalence of dental caries and the intellectual ability of children. Method: In this cross-sectional study, 161 children from 9 to 10 years of age were evaluated. The concentration of fluoride in drinking water and urine was
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