Abstract
This paper reports the effect of chronic high fluoride exposure on children’s intelligence quotient (IQ). In this cross sectional study, two urban communities with similar socio-economic and cultural status but with different levels of fluoride in drinking water, in Kerman province of Iran were studied: Koohbanan City (fluoride 2.38 mg/L), Baft City (fluoride 0.41 mg/L). Study samples consisted of 119 children 6 to 9 years old: 50 children from Koohbanan and 60 children from Baft. Raven’s progressive matrices used to determine the effect of fluoride exposures on children’s IQ. The statistical analysis was carried out using the t-test, the chi-square test and the Mann-Whiteney test. In the low fluoride area (control group), the mean IQ score of children was 97.80±15.95 that decreased to 91.37±15.63 for the high fluoride group (Koohbanan’s children), it was significantly different from the control group (P<0.05). Although fluoride is widely promoted for prevention of dental caries, its overconsumption may lead to dental fluorosis and other adverse effects. Based on the findings, the chronic exposure to high levels of fluoride can be one of the factors that influence intellectual development. Therefore, it is necessary to think about some solutions for preventing the bad effects of excessive intake of fluoride ion to the body, especially in cities like Koohbanan.
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Relationship between Drinking Water Fluoride and Intelligence Quotient in Egyptian School Children.
Background: Fluoridation of drinking water, despite being regarded as one of the top ten public health achievements of the twentieth century, has remained a much more debated concept. Excessive fluoride intake during infancy and early childhood causes a number of irreversible structural and functional changes in the CNS leading to
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Letter to the Editor: IQ of 9-12 year-old children in high and low-drinking water fluoride areas in West Axerbaijan Province, Iran: Further information on the two villages in the study and the confounding factors considered.
In a critique of our study1 on the IQ of 9–12-year-old children in high- and low drinking water fluoride (F) areas in West Azerbaijan province, Iran, Dr Ken Perrott questioned whether possible confounding factors in the two villages, such as the rural status and parental educational levels, were adequately considered.2 Perrott’s
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The cholinergic system, intelligence, and dental fluorosis in school-aged children with low-to-moderate fluoride exposure.
Highlights Low-to-moderate fluoride was associated with alterations of cholinergic system. The prevalence of dental fluorosis (DF) was related to cholinergic system. AChE was negatively associated with children’s intelligence quotient (IQ). AChE mediates association of fluoride with DF prevalence and lower odds of IQ > 120. DF and IQ were
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Comparative assessment of the physical and mental development of children in endemic fluorosis area with water improvement and without water improvement.
Tests were performed to compare the IQ and physical development of 7-to-14-year-old children from endemic fluorosis areas, with and without water improvement programs, with children from a nonfluorosis area. The results showed that the average IQ of children in each age group from the fluorosis area without water improvement is lower than those
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Effect of high-fluoride water supply on children’s intelligence.
In Shanxi Province, China, children living in the endemic fluoride village of Sima (water supply F = 4.12 mg/L) located near Xiaoyi City had average IQ (97.69) significantly lower (p < 0.02) than children living to the north in the nonendemic village of Xinghua (F = 0.91 mg/L; average IQ = 105.21). These differences were not
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Fluoride & IQ: 76 Studies
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
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Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
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Fluoride's Direct Effects on Brain: Animal Studies
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