Abstract
This study was conducted on 160 children, in the Bagalkot district of Karnataka state between August and October 2010, with the aim of finding out if there is a relation between dental fluorosis status and Intelligence Quotient (IQ). Children were categorized as, those suffering from dental fluorosis and those not suffering from dental fluorosis and for all children in both categories, Intelligence testing was done using the Raven’s Coloured Progressive Matrices. The following observations were made from the data gathered: The mean IQ score of children without dental fluorosis was significantly higher than those children who had dental fluorosis. The mean IQ scores did not vary with the severity of dental fluorosis as classified by Dean’s fluorosis index. Also it was noticed that the percentage of children with dental fluorosis was more in Extremely Low and Low IQ categories whereas the percentage of children without dental fluorosis was more in Average and High Average IQ categories. Previous studies had indicated toward decreased Intelligence in children exposed to high levels of fluoride and our study also confirmed such an effect.
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Investigation of Intelligence Levels of Children of 8 to 12 Years of Age in Coal Burning-Related Endemic Fluorosis Areas.
Objective: To investigate the relationship between age, dental fluorosis and intelligence in children aged 8-12 in coal-burning fluorosis (CBF) area, Guizhou province. Methods: A cross-sectional study was conducted to investigate the prevalence of dental fluorosis and intellectual level in 284 children (n=167 for CBF area, n=120 for control are) aged 8-
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Fluoride exposure and children’s intelligence: Gene-environment interaction based on SNP-set, gene and pathway analysis, using a case-control design based on a cross-sectional study.
Highlights High intelligence was inversely correlated with water, urinary, hair and nail fluoride. Fluoride interacts with a SNP-set of rs3788319, rs1879417, rs57377675, rs11556505 and rs7187776 on intelligence. Fluoride interacts with mitochondrial function-related genes CLU and TOMM40 on intelligence. Multiple neurodevelopmental pathways related to metabolism may be involved in the
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Study of cognitive function impairment caused by chronic fluorosis.
Objective: To investigate whether an impairment in cognitive function exists in patients diagnosed with fluoride poisoning as well as its biological basis. Methods: Individuals suffering from fluoride poisoning from a high fluorine region were selected for the study group, while healthy individuals from a nonendemic region were selected as the control group. Using
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Effect of fluoride in drinking water on children's intelligence in high and low fluoride areas of Delhi
Introduction: Fluoride is one of the indispensable elements for the living being. However, the intake of F above the threshold level can affect the central nervous system even before causing dental or skeletal fluorosis. Aim: The aim was to assess the effect of fluoride in drinking water on the intelligence quotient
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Relation Between Intelligence and COMT Gene Polymorphism in Children Aged 8-12 in the Endemic Fluorosis Area and Non-Endemic Fluorosis Area.
1.1 Subjects According to the principle that a selected population lives in a similar natural environment and has similar lifestyle and diet habits, one township in the endemic fluorosis area and one township in the non-endemic fluorosis area in a certain region were respectively selected as sites for population sampling. In
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
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