Abstract
Objective: Investigate the effect of high fluoride exposure on the level of intelligence in children.
Method: In May 2006, 42 children from a high endemic fluorosis group and 37 children from the control area (who have been consuming low-fluoride water after water improvement schemes) were chosen for the test. They are all from a primary school in Pucheng county, Shaanxi province. Their level of intelligence was tested, and a test for dental fluorosis was conducted using Dean’s method, and the level of fluoride in urine was determined with a fluoride ion selective method.
Results: The average intelligence level of the children in the high fluoride group (96.11 + 12.00) was lower than that of the control group (98.41 + 14.75). We have not found any children with an intelligence level exceeding a level deemed as excellent; as for the intelligence distribution in these groups, there is little statistical significance. There was a negative correlation between the urine fluoride concentration and the level of intelligence in children (P>0.05).
Conclusion: Exposure to high levels of fluoride is likely to cause a certain level of harm.
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Effect of high water fluoride concentration on the intellectual development of children in Makoo/Iran.
OBJECTIVE: Prolonged excessive intake of fluoride during child's growth and development stages has been associated with mental and physical problems. The aim of this study was to investigate the effect of excessive fluoride intake on the intelligence quotient (IQ) of children living in five rural areas in Makoo/Iran. MATERIALS AND METHODS:
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Studies of relationships between the polymorphism of COMT gene and plasma proteomic profiling and children’s intelligence in high fluoride areas
Part I – Effect of high F drinking water on children’s IQ Objective: To investigate the relationships among the children’s serum F, urine F, thyroid hormone levels and children’s IQ in the high fluoride areas. Methods: We collected the samples of the drinking water, urine and blood and measured the F concentrations,
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Assessment of intelligence quotient among schoolchildren of fishermen community of Kutch, Gujarat, India
Background and aim: The aim of the study was to assess the intelligence quotient of fishermen schoolchildren of Kutch, Gujarat, India. Materials and methods: A descriptive cross-sectional study was conducted among 8 to 10 years old schoolchildren living in Kutch District, Gujarat, India, from January to February 2013. Seguin Form Board
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Fluoride exposure and intelligence in school-age children: evidence from different windows of exposure susceptibility.
Study Retracted on November 8, 2022. Retraction Note: BMC Public Health 20, 1657 (2020) https://doi.org/10.1186/s12889-020-09765-4 The Editor has retracted this article. After publication, concerns were raised regarding the data analysis and conclusions in the paper. The authors have provided raw data, and post-publication review found inconsistencies in methodology and major misinterpretation of the
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Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects.
BACKGROUND AND AIM: People of all ages are exposed to fluoride from a variety of sources including dental products, drinking water, food, beverages and pharmaceuticals. In some developed countries, fluoride is added to municipal water systems to prevent tooth decay. The National Toxicology Program (NTP) conducted a systematic review of
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Fluoride Affects Learning & Memory in Animals
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Fluoride & IQ: 76 Studies
• As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies which reported an association of reduced IQ with exposure
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Fluoride's Direct Effects on Brain: Animal Studies
The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
The NRC's analysis on fluoride and the brain.
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Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
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