Abstract

Objective: Try to find out the effects of high iodine and high fluorine on children’s intelligence and thyroid function.

Methods: We selected in Qingyun County the Lidian Primary School, where the iodine and fluorine in the water are relatively high in concentration as the investigative point and Dading Primary School where the iodine and fluorine in the water have normal concentration as the control point. The high iodine goiter rate, dental fluorosis, IQ and thyroid metabolism indicators of the students aged 8 to 12 from the two schools were examined.

Results: In high iodine and high fluorine areas, the goiter rate and dental fluorosis of 8~12 years children were 29.8% and 72.98%. The children’s average intelligence quotient (IQ) was 76.67±7.75, slightly lower than comparison point, but low intelligent pupil was 16.67%. The urinary iodine and urinary fluoride were (816.25±1.80) ?g/L and (3.08±1.03)mg/L separately, clearly higher than comparison point. The thyroid iodine131 uptake rates were visible lower. The value of 3h and 24h were respectively (9.36±1.55)% and (9.26±4.63)%. The serum TSH level was obviously higher than comparison point.

Conclusions: High iodine and high fluorine have certain influence on children’s intelligence and thyroid function.

• Related Studies :

  • The effects of high levels of fluoride and iodine on intellectual ability and the metabolism of fluoride and iodine.

    The authors carried out a study on the intellectual abilities and fluoride/iodine metabolism of children living in a high fluoride-high iodine area. Among the results: the percentage of the general population living in this fluoride/iodine-contaminated region that suffered from goiter (clinical thyroid enlargement) was 3.8%, the rate of children already showing some thyroid

  • The relationships between thyroid-stimulating hormone and/or dopamine levels in peripheral blood and IQ in children with different urinary iodine concentrations.

    Highlights TSH is not related IQ in children with different urinary iodine concentrations. Dopamine in plasma is unrelated to IQ in children with adequate or excessive iodine. Dopamine has positive correlation with intelligence in iodine deficiency group. The interaction between dopamine in plasma and TSH is not related to

  • The effect of fluorine on the level of intelligence in children.

    Recently, many researchers and scholars have studied about the effects of the trace element, iodine, on the level of intelligence in children. However there has been little coverage or noise about the same effect of fluorine on children. For this purpose we have performed some research and the results are as follows.

  • Fluoride-induced developmental disorders and iodine deficiency disorders as examples of developmental disorders due to disturbed thyroid hormone metabolism.

    Both exposure to fluoride and iodine deficiency during early development can lead to disturbed thyroid hormone metabolism and produce the same spectrum of developmental disorders including short stature, bone deformities, cognitive impairment, delayed dental eruption, and dental fluorosis. The levels of creatinine-adjusted urinary fluoride experienced by pregnant women in areas

  • The relationship of a low-iodine and high-fluoride environment to subclinical cretinism in Xinjiang.

    Cretinism in iodine-deficiency areas is well known, yet the milder forms of somatic and psychomotor maldevelopment and thyroid dysfunction caused by iodine deficiency may be more difficult to detect. DeQuervain, in 1936, called this milder form "semi-cretinism," while in 1980 Laggasse used the term "cretinoidism." It was formally named "subclinical

• Related FAN Content :

  • Fluoride, Water Hardness, and Endemic Goitre

    Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.

  • Fluoride's Impact on Thyroid Hormones

    Up through the 1950s, doctors in Europe and South America prescribed fluoride for this purpose in patients with hyperthyroidism. (Merck Index 1968). Fluoride was selected as a thyroid suppressant based on findings dating back to the mid-19th century that fluoride is a goitrogen (a substance that can cause goiter). When used as

  • The Relationship Between Fluoride Exposure & Goitre in South Africa

    As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.

  • Fluorine in the Aetiology of Endemic Goitre

    The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.

  • Nutrient Deficiencies Enhance Fluoride Toxicity

    It has been known since the 1930s that poor nutrition enhances the toxicity of fluoride. As discussed below, nutrient deficiencies have been specifically linked to increased susceptibility to fluoride-induced tooth damage (dental fluorosis), bone damage (osteomalacia), neurotoxicity (reduced intelligence), and mutagenicity. The nutrients of primary importance appear to be calcium,