Abstract
OBJECTIVES: To compare the prevalence and severity of developmental defects of enamel (DDE) among subjects whose maxillary incisors developed during periods with different concentrations of fluoride in the public water supply.
METHODS: Standardized intra-oral photographs of random samples of 12-year-old children were collected in 1983, 1991 and 2001 (n = 1,990) in Hong Kong and assessed for DDE by a trained masked examiner. The fluoride concentrations in the public water supply at the times when the enamel on their maxillary incisors developed were 1.0, 0.7 and 0.5 ppm, respectively.
RESULTS: The mouth prevalence of DDE for these children (based on the maxillary incisors) were 92.1, 55.8 and 35.2% in the years 1983, 1991 and 2001, respectively (p < 0.001). Most of these children were affected by diffuse opacities (89.3% in 1983, 48.5% in 1991 and 32.4% in 2001, p < 0.001). Marked differences in the mean number of teeth affected by DDE (p < 0.001) and in the maximum extent of DDE (p <or= 0.002) between 1983, 1991 and 2001 were also observed.
CONCLUSIONS: A decrease in the prevalence and severity of DDE among the maxillary incisor teeth of the children corresponded to the reductions in the concentration of fluoride in the water during the time of enamel development.
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Use of the fluorosis risk index in a cohort study: the Iowa fluoride study
OBJECTIVES: Several studies have used the Fluorosis Risk Index (FRI) to assess risk factors for dental fluorosis. This study reports fluorosis prevalence estimates in a birth cohort using the FRI in different ways. METHODS: Subjects (n=443) were participants in the Iowa Fluoride Study, a birth cohort study of fluoride exposures
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Prevalence of dental fluorosis in fluoridated and nonfluoridated communities--a preliminary investigation
As a result of undocumented observations that the prevalence of dental fluorosis in both fluoridated and nonfluoridated communities may be higher than would be predicted on the basis of Dean's data from the 1940s, dental fluorosis assessments using a modification of Dean's Index were made in 1981 as part of
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The prevalence and risk factors of fluorosis among patients in a pediatric dental practice
Seven hundred eight patients aged 5-19 years in a pediatric practice in North Carolina were selected using a random-start, systematic sampling procedure and enrolled in a case control study to determine risks for fluorosis. Subjects were examined by four trained examiners using the Tooth Surface Index of Fluorosis (TSIF). Information
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Diffuse opacities in 12-year-old Hong Kong children - four cross-sectional surveys
OBJECTIVES: To compare the prevalence and severity of diffuse opacities among subjects whose maxillary incisors developed during periods with different concentrations of fluoride in the Hong Kong public water supply. METHODS: Standardized intra-oral photographs of random samples of 12-year-old children were collected in 1983, 1991, 2001 and 2010 (n = 2658)
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Fluoride metabolism and fluorosis.
OBJECTIVES: This paper is primarily concerned with the only proven risk associated with water fluoridation: enamel fluorosis. Its purpose is to review current methods of measuring enamel fluorosis, its aetiology and metabolism. A further objective is to identify risk factors to reduce the prevalence of enamel fluorosis and employ methods
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Dental Fluorosis in the U.S. 1950-2004
Before the widespread use of fluoride in dentistry, dental fluorosis was rarely found in western countries. Today, with virtually every toothpaste now containing fluoride, and most U.S. water supplies containing fluoride chemicals, dental fluorosis rates have reached unprecedented levels. In the 1950s, it was estimated that only 10% of children in
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Diagnostic Criteria for Dental Fluorosis: The Thylstrup-Fejerskov (TF) Index
The traditional criteria (the "Dean Index") for diagnosing dental fluorosis was developed in the first half of the 20th century by H. Trendley Dean. While the Dean Index is still widely used in surveys of fluorosis -- including the CDC's national surveys of fluorosis in the United States -- dental
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Racial Disparities in Dental Fluorosis
In 2005, the Centers for Disease Control published the results of a national survey of dental fluorosis conducted between 1999 and 2002. According to the CDC, black children in the United States have significantly higher rates of dental fluorosis than either white or Hispanic children. This was not the first time that black children were found to suffer higher rates of dental fluorosis. At least five other studies -- dating as far back as the 1960s -- have found black children in the United States are disproportionately impacted by dental fluorosis.
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Dental Fluorosis Is a "Hypo-mineralization" of Enamel
Teeth with fluorosis have an increase in porosity in the subsurface enamel ("hypomineralization"). The increased porosity of enamel found in fluorosis is a result of a fluoride-induced impairment in the clearance of proteins (amelogenins) from the developing teeth. Despite over 50 years of research, the exact mechanism by which fluoride impairs amelogin
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