Abstract
The relation between trace element levels in drinking water and cognitive function was investigated in a population-based study of elderly residents (n = 1,016) in rural China in 1996-1997. Cognitive function was measured using a Chinese translation of the Community Screening Interview for Dementia. A mixed effects model was used to evaluate the effect of each of the elements on cognitive function while adjusting for age, sex, and educational level. Several of the elements examined had a significant effect on cognitive function when they were assessed in a univariate context. However, after adjustment for other elements, many of these results were not significant. There was a significant quadratic effect for calcium and a significant zinc-cadmium interaction. Cognitive function increased with calcium level up to a certain point and then decreased as calcium continued to increase. Zinc showed a positive relation with cognitive function at low cadmium levels but a negative relation at high levels.
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Neuroprotective influence of taurine on fluoride-induced biochemical and behavioral deficits in rats.
Highlights Influence of taurine was studied in rat model of fluoride neurotoxicity. Taurine reversed the fluoride-induced neurobehavioural deficits. Taurine decreased intracellular hydrogen peroxide and lipid peroxidation levels. Taurine reversed the fluoride-induced inhibition of acetylcholinesterase activity. Taurine may be a potential therapeutic agent in fluoride-mediated neurotoxicity. Epidemiological and experimental studies have
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[Effects of chronic fluorosis on neurobehavioral development in offspring of rats and antagonistic effect of Vitamin E]
Objective: To study the effect of chronic fluorosis on neurobehavioral development, the ability of learning and memory in offspring of rats, and the antagonistic effect of antioxidant Vitamin E (Vit E). Methods: According to body weight, forty-five 1-month-old Sprague-Dawley (SD) rats of 30 females and 15 males were divided into three
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Effects of high iodine and high fluorine on children’s intelligence and thyroid function.
Objective: Try to find out the effects of high iodine and high fluorine on children’s intelligence and thyroid function. Methods: We selected in Qingyun County the Lidian Primary School, where the iodine and fluorine in the water are relatively high in concentration as the investigative point and Dading Primary School where the iodine and
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The relationships between thyroid-stimulating hormone and/or dopamine levels in peripheral blood and IQ in children with different urinary iodine concentrations.
Highlights TSH is not related IQ in children with different urinary iodine concentrations. Dopamine in plasma is unrelated to IQ in children with adequate or excessive iodine. Dopamine has positive correlation with intelligence in iodine deficiency group. The interaction between dopamine in plasma and TSH is not related to
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The effect of fluorine on the level of intelligence in children.
Recently, many researchers and scholars have studied about the effects of the trace element, iodine, on the level of intelligence in children. However there has been little coverage or noise about the same effect of fluorine on children. For this purpose we have performed some research and the results are as follows.
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Fluoride Exposure Increases Metabolic Requirement for Calcium & Vitamin D
It is well known that individuals with nutrient deficiencies are more susceptible to fluoride toxicity, including fluoride's bone effects. As discussed in the following studies, fluoride increases the skeleton's need for calcium (and vitamin D) by increasing the amount of unmineralized tissue (osteoid) in the bone. When insufficient calcium and
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Fluoride's Direct Effects on Brain: Animal Studies
The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
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Fluoride & IQ: 76 Studies
• As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies which reported an association of reduced IQ with exposure
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Fluoride Exposure Increases Metabolic Requirement for Magnesium
Fluoride's toxicity is significantly enhanced in the presence of nutritional deficiencies. Similarly, fluoride exposure increases the body's requirement for certain nutrients. An individual with a high intake of fluoride, for example, will need a proportional increase in calcium to avoid the mineralization defects (e.g., osteomalacia) that fluoride causes to bone
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