Abstract
The effect of fluoride on murine thyroid function and cerebellar development was studied by administering NaF in drinking water (0.5 g/L) to pregnant and lactating mice, from the 15th day of pregnancy to the 14th day after delivery. Compared to a control group, the NaF-treated pups, at age 14 days, showed a 35% decrease in body weight, a 75% decrease in plasma free T4, and reductions in the cerebellar and cerebral protein concentrations by 27% and 17%, respectively. Consistent histological changes were present in the cerebellum of the treated mice with the external granular layer being markedly reduced or absent, the Purkinje cell bodies being poorly differentiated and arranged in a single layer at the surface of the internal granular layer, and with more apoptotic Purkinje cells being present.
-
-
Fluoride toxicity and status of serum thyroid hormones, brain histopathology, and learning memory in rats: a multigenerational assessment.
High-fluoride (100 and 200 ppm) water was administered to rats orally to study the fluoride-induced changes on the thyroid hormone status, the histopathology of discrete brain regions, the acetylcholine esterase activity, and the learning and memory abilities in multigeneration rats. Significant decrease in the serum-free thyroxine (FT4) and free triiodothyronine (FT3)
-
The effect of fluorine on the level of intelligence in children.
Recently, many researchers and scholars have studied about the effects of the trace element, iodine, on the level of intelligence in children. However there has been little coverage or noise about the same effect of fluorine on children. For this purpose we have performed some research and the results are as follows.
-
Effects of high iodine and high fluorine on children’s intelligence and thyroid function.
Objective: Try to find out the effects of high iodine and high fluorine on children’s intelligence and thyroid function. Methods: We selected in Qingyun County the Lidian Primary School, where the iodine and fluorine in the water are relatively high in concentration as the investigative point and Dading Primary School where the iodine and
-
Effects of fluoride exposure on thyroid hormone level and intelligence in rats
Objective: To investigate the effects of fluoride exposure on the thyroid hormone level and intelligence in rats and to investigate the biomarkers of intellectual impairment induced by high fluoride exposure. Methods: A total of 24 clean healthy Sprague-Dawley rats were randomly divided into control group (tap water containing 0.344 mg/L fluoride)
-
Effects of fluoride on psychomotor performance and memory of aluminum potroom workers
In this cross-sectional study, the psychomotor performance and memory skills of a fluoride-exposed group (FEG) of 64 male workers in an aluminum potroom were compared with those of 60 male workers in a nonfluoride-exposed group (NFEG). The FEG had a mean age of 37.59±4.82 yr and had been employed for
Related Studies :
-
-
-
Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
-
Fluoride's Impact on Thyroid Hormones
Up through the 1950s, doctors in Europe and South America prescribed fluoride for this purpose in patients with hyperthyroidism. (Merck Index 1968). Fluoride was selected as a thyroid suppressant based on findings dating back to the mid-19th century that fluoride is a goitrogen (a substance that can cause goiter). When used as
-
Fluorine in the Aetiology of Endemic Goitre
The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.
-
Fluoride Aggravates Thyroid Damage Caused by Excess Iodine Intake
Chinese researchers have found that the combination of excess fluoride with excess iodine caused greater reductions in IQ, or greater increases in goitre than either scenario by itself.
-
The Relationship Between Fluoride Exposure & Goitre in South Africa
As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.
Related FAN Content :
-