Abstract
The effect of prolonged administration of NaF on the metabolism of (guinea pig) Purkinje cells in the cerebellar cortex was studied by histochemical methods. Experimentation showed an intensification of the metabolic activity of the mitochondria and probably of the membrane system of the endoplasmic reticulum, activation of the complex of enzymes connected with active transport through membrane structures of cells and the absence of perceptible changes in the process of protein synthesis in experimental animals as compared with controls. The intensified activity of the enymatic complexes is probably connected with the excitation of the neurons provoked by the introduction of a toxic substance.
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Effect of maternal exposure of fluoride on biometals and oxidative stress parameters in developing CNS of rat.
Excessive intake of essential elements agitates elemental homeostasis resulting in their heterogeneous distribution. Distraction of these elements in central nervous system (CNS) have been demonstrated in many neurological disorders, which are vital in generating free radicals, causing oxidative stress, and contributing to neuronal maladies. The developing CNS is highly vulnerable
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Study of cognitive function impairment caused by chronic fluorosis.
Objective: To investigate whether an impairment in cognitive function exists in patients diagnosed with fluoride poisoning as well as its biological basis. Methods: Individuals suffering from fluoride poisoning from a high fluorine region were selected for the study group, while healthy individuals from a nonendemic region were selected as the control group. Using
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Health problems in fluoride endemic areas of Gaya District
Fluoride (F) was estimated in the groundwater of six blocks (Bodh Gaya, Manpur, Wazirganj, Belaganj, Amas, and Bankebazar) of Gaya District, Bihar, for different physio-chemical properties e.g. pH, total dissolved solids(TDS), conductivity, turbidity, total hardness (TH), calcium, magnesium, iron and fluoride. Morever 93 blood samples from different age groups including
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[Effects of fluoride and arsenic in drinking water on children's intelligence].
Objective: To study the effect of fluoride and arsenic exposure in drinking water on children’s intelligence ,and to provide scientific basis for children’s health protection. Methods: Two hundred and sixty-eight pupils in Hangjinhou Qi,Inner Mongolia were selected as subjects. Fluoride and arsenic in drinking water were determined. The Chinese combined Raven’s
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Brain mapping of mentally retarded children in high-fluoride regions
On the basis of routine EEG, this article used mapping technologies to conduct research on the brain electrical activities of mentally retarded children in high-fluoride regions. Results showed that the O energy percentages in the central, parietal, occipital, and left temporal areas of the mentally retarded group were significantly higher
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Fluoride Affects Learning & Memory in Animals
An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out
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Fluoride & IQ: 76 Studies
Note: See the Updated list of fluoride IQ studies at https://fluoridealert.org/researchers/fluoride-iq-studies/the-fluoride-iq-studies/ • As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
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Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
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Fluoride's Direct Effects on Brain: Animal Studies
The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.
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