Abstract
We report a case of fluorosis due to high water and soil contents in a 23-year-old Algerian woman. The condition, which is infrequent at this age, was promoted by chronic renal failure due to a congenital renal malformation. Roentgenograms showing osteosis with increased bone density were suggestive of fluorosis rather than renal osteodystrophy. Bone tissue fluoride assay confirmed fluorosis. Histomorphometric analysis of bone biopsy specimens showed mixed lesions: major osteocondensation due to bone fluorosis and morphologic and dynamic osteomalacia related to the chronic renal failure.
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Enamel hypoplasia in children with renal disease in a fluoridated area
The aim of this study was to compare the frequency of enamel hypoplasia in children with renal disease and healthy children, all of whom live in a fluoridated area. A cross-sectional study was made in 42 children divided into 2 groups. To describe enamel changes, 3 diagnostic criteria were applied:
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Fluoride aggravation of oxidative stress in patients with chronic renal failure.
Based on evidence that fluoride ion (F) increases the production of reactive oxygen species, inhibits antioxidant enzyme activity, and enhances lipid peroxidation, a study of these effects was conducted on 52 patients with chronic renal failure (CRF), of whom 33 were under going chronic haemodialysis (HD) with the use of polysulphone membrane dialysers, while 19 with
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Fluoride metabolism and renal osteodystrophy in regular dialysis treatment
Fluoride in plasma, urine and bone tissue ash were estimated using a fluoride-ion electrode in 20 control persons (CP), 32 patients with compensated chronic renal failure (CRFP) and 59 patients in RDT (RDTP). The increase in plasma fluoride (CP: 2.4 +/- 1.4, CRFP: 6.5 +/- 2.2, RDTP: 12.3 +/- 4.5
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High fluoride concentrations in the serum and bone of patients with chronic renal failure
The aim was to study the effect of ingested fluoride in patients with chronic renal failure (CRF). Serum fluoride concentrations were measured in 104 subjects, who formed three groups: nondialyzed CRF, dialyzed CRF, and a control group. The iliac bone fluoride was measured in 20 subjects. Serum, urine and water
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Bone fluoride concentrations after 16 years of drinking water fluoridation
The fluoride content of 147 pieces of vertebral cancellous bone, collected at autopsy from long-term residents in Basle, Switzerland, was determined. A statistical analysis of the results sustained the hypothesis of age-dependent fluoride accumulation in bone. No differences were found between sexes. 4 cases with severe chronic pyelonephritis had definitely
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Annapolis: Water Fluoridation Linked to Death of Dialysis Patient
EVENING CAPITAL (Annapolis, Maryland) November 29, 1979 Fluoride Linked to Death by Mary Ann Kryzankowicz Staff Writer Fluoride poisoning has been definitely linked to the death of a 65-year-old kidney dialysis patient who became ill during a blood cleaning process Nov 11. State Medical Examiner Dr. (illegible) Guard has ruled that Lawrence Blake, 65, of Arundel
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Skeletal Fluorosis in the U.S.
Although there has been a notable absence of systematic studies on skeletal fluorosis in the U.S., the available evidence indicates that the consumption of artificially fluoridated water is likely to cause skeletal fluorosis and other forms of bone disease in people with kidney disease and other vulnerable populations.
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Dental Fluorosis & Enamel Hypoplasia in Children with Kidney Disease
Children with kidney disease are known to have high levels of fluoride in their blood and to be at risk for disfiguring tooth defects. Research suggests that high levels of fluoride in blood, which can cause the tooth defect known as dental fluorosis, can contribute to the defects that occur
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Exposure Pathways Linked to Skeletal Fluorosis
Excessive fluoride exposure from any source -- and from all sources combined -- can cause skeletal fluorosis. Some exposure pathways , however, have been specifically identified as placing individuals at risk of skeletal fluorosis. These exposure pathways include: Fluoridated Water for Kidney Patients Excessive Tea Consumption High-Fluoride Well Water Industrial Fluoride Exposure Fluorinated Pharmaceuticals (Voriconazole
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Kidney Patients Are at Increased Risk of Fluoride Poisoning
It is well established that individuals with kidney disease are susceptible to suffering bone damage and other ill effects from low levels of fluoride exposure. Kidney patients are at elevated risk because when kidneys are damaged they are unable to efficiently excrete fluoride from the body. As a result, kidney patients
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