Fluoride Action Network


17 rats with chronic fluorosis induced by prolonged drinking of water containing 50 ppm fluorine and 17 rats drinking low-fluorine water served as control were used to study the DNA and RNA contents of heart, liver and kidney. The findings suggest that excessive accumulation of fluorine can suppress the synthesis of RNA of heart, liver and kidney and reduce its content accordingly but can not influence the DNA synthesis of mature organs in vivo.