Abstract

As part of our study on the toxic effects of deltamethrin and fluoride (F) on antioxidant parameters in rats, hematological effects of these chemicals were evaluated in the same animals. Deltamethrin and F produced a marked decrease in the hematological parameters including total erythrocyte count, hemoglobin, packed cell volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and total leukocyte count. Among alterations in the leukocytes, lymphopenia, neutrophilia, and eosinopenia were observed. Exposure of the rats to both deltamethrin and F together gave the greatest changes.

NOTE FROM FAN: Deltamethrin is a brominated pyrethroid insecticide. The specific foods that this pesticide is approved for in the U.S. are here.

• Related Studies :

  • Haematological alterations induced by subchronic oral exposure of buffalo calves to fipronil and fluoride.

    A study is reported on haematological alterations in buffalo calves from subchronic oral exposure to the pesticide fipronil, sodium fluoride alone, and the two in combination. Twenty-four male buffalo calves, 6 to 12 months old, were divided into 4 groups of 6 animals each. Group I without treatment served as

  • Arsenic and fluoride co-exposure affects the expression of apoptotic and inflammatory genes and proteins in mononuclear cells from children

    Humans may be exposed to arsenic (As) and fluoride (F) through water consumption. However, the interaction between these two elements and gene expression in apoptosis or inflammatory processes in children has not been thoroughly investigated. Herein, the expression of cIAP-1, XIAP, TNF-?, ENA-78, survivin, CD25, and CD40 was evaluated by

  • Synergistic effect of sodium fluoride and cypermethrin on the somatic index and histopathology of albino mice testes.

    Male albino mice were treated at 48-hr intervals with cypermethrin and sodium fluoride (NaF), separately and in combination, for 15 and 30 days with 1/10th of the single LD50 dosage of cypermethrin and NaF for individual administration by oral gavage (i.e., 8.5 mg/kg bw and 5.6 mg/kg bw, respectively) and

  • Effect of deltamethrin and fluoride co-exposure on the brain antioxidant status and cholinesterase activity in Wistar rats

    The study evaluated the effect of commercial preparation of deltamethrin, Butox®, and fluoride (F-) co-exposure on the brain antioxidant status and cholinesterase activity in rats. Group A was untreated. Group B was gavaged Butox®, providing deltamethrin at the dose rate of 1.28 mg per kg body weight per day. Group

  • Effect of high fluorine (F) intake on tissue lead (Pb) concentrations

    Four groups of 10 male, albino Sprague Dawley rats receiving either deionized water or deionized water containing 300 parts per million (ppm) F as NaF, 200 Pb as Pb acetate or F+Pb at 300 and 200 ppm, respectively,  as drinking water for 10 weeks were fed a casein-based purified diet.

• Related FAN Content :

  • Fluoride Levels and Fluoride Contamination of Fruit Juices

    "Forty-three ready-to-drink fruit juices were examined for fluoride ion concentration. It was found that 42% of the samples had more than 1 ppm of fluoride. It was also determined that "pure" fruit juices, often grape juices, contained high levels of fluoride. . . . Since it is common practice to use fluoride-containing insecticide in growing grapes, it is believed that contamination of these juices is occurring."