Complete fluoride intake data from the 2000-2003 UK National Diet and Nutrition Survey were used to examine questions outstanding from the Fluoridation of Water Supplies review process. In a quarter of the population, fluoride consumption from all sources exceeds the Safe Intake defined by the Committee on the Medical Aspects of Food Policy, regardless of water fluoride concentration. In areas supplied with fully fluoridated water, fluoride intake exceeds the recommended safe maximum in nearly two thirds of consumers. The implications are discussed and recommendations are made.
Maternal fluoride exposure, fertility and birth outcomes: The MIREC cohort.
Abstract Objective : Fluoride exposure >1.5 mg/L from water has been associated with adverse pregnancy and birth outcomes. Little is known, however, about the effect of fluoride at levels consistent with water fluoridation (i.e., 0.7 mg/L) on pregnancy and birth outcomes. We examined the relationship between maternal fluoride exposure, fertility, and birth
Total fluoride intake and excretion in children up to 4 years of age living in fluoridated and non-fluoridated areas.
Fractional fluoride retention is important during the early years of life when considering the risk of development of dental fluorosis. This study aimed to measure fractional fluoride retention in young children. The objectives were to investigate the relationships between fractional fluoride retention and total daily fluoride intake, age, and body
Fluoride metabolism in man
Fluoride balances were measured in man under strictly controlled dietary conditions before and during the intake of sodium fluoride, and after its discontinuation. Fluoride intake averaged 4.4 mg/day in the control period and 13.8 mg during the addition of an average of 21 mg sodium fluoride/day. The main pathway of
Effects of water improvement and defluoridation on fluorosis-endemic areas in China: A meta-analysis.
Highlights The first analysis of the effect of improving water quality and reducing fluoride in China over 40 years. Analysis of the effect of water improvement and fluoride reduction in different provinces of China. We analyzed the effect of water improvement on dental fluorosis, skeletal fluorosis, and fluoride content
[Biological exposure limits caused by co exposure to fluoride and arsenic based on Wnt signaling pathway].
Chronic fluoride-arsenic combined poisoning is a global public health problem. While the cause of the disease is clear, the pathogenesis is unknown. Given that there is no specific treatment, early prevention is particularly important. Biological exposure limits are designed to investigate the maximum allowable concentration of harmful effects from exogenous
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