HF exposure might produce adverse effects in industrial workers. A 3 mo. exposure of rats to HF at 10 mg/m3 8 h/day 5 days/wk resulted in increased blood serum concentrations of hydroxyproline and hydroxylysine and in enhanced urinary excretion of these amino acids and in changes of collagen fractions in the liver, lungs and skin. In all tissues studied (especially liver), soluble and insoluble collagen decreased. HF affected biosynthesis and maturation of collagen fibers.
Influence of fluoride compounds upon connective tissue metabolism in growing rats: 1. Effect of hydrofluoride on collagen metabolism.
Female rats were exposed to hydroxyfluoride (2.7 mg/m3 or 5.0 mg/m3) seven weeks before pregnancy during pregnancy and lactation as well as subsequently with the offsprings up to 1, 2, 4 and 6 months after birth. The offspring was taken for investigations. It was found that serum hydroxyproline and hydroxylysine
Effects of inhaled HF on lipid metabolism in guinea pigs.
The effects of exposure to inhaled hydrogen-fluoride (7664-39-3) (HF) on lipid metabolism were investigated in male albino-guinea-pigs. One group of animals was exposed to 10 milligrams per cubic meter (m3) HF in a cylindrical plexiglass cage with an air turnover rate of 40m3 per hour for 8 hours. A control
Oxidative stress parameters in rats exposed to fluoride and caffeine
In our experiment, the 1-month effects of caffeine (Caff) and fluoride (F) administered separately and together on nitric oxide and total antioxidant status in serum, brain, liver and kidney of rats were investigated. Also, the influence of caffeine on fluoride excretion with urine was studied. Thirty adult male Wistar rats
Effect of fluoride on enzymes from serum, liver, kidney, skeletal and heart muscles of mice.
White mice maintained on water containing 100 ppm NaF showed changes in the enzyme level in serum, liver, kidney, heart and skeletal muscles. Enzymes studies were alkaline phosphatase (ALP), acid phosphatase (AcP), glutamate-oxalacetate transaminase (GOT), glutamate-pyruvate transaminase (GPT), lactic dehydrogenase (LDH), isocitric dehydrogenase (ICDH) and cholinesterase (CE). AcP was markedly
[Hydrofluoric acid injury analysis on the health of workers].
Objective: To analyze the damage caused by hydrofluoric acid to the health of operating workers and to explore health monitoring indicators. Method: Occupational health examinations were carried out on 536 hydrofluoric acid operating workers from the etching process at a certain factory, and 256 persons in the control group. Results: Among the
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