The prognosis for fluoride inhalation is poor, owing to the extreme toxicity of the substance and lack of satisfactory treatment. In the case of massive inhalation, the slow, progressive destruction of the bronchial mucosa and lung tissue will be lethal. Irrespective of the dose, a transient restriction in renal function or acute renal failure will occur. The transient increase in transaminase seems to be caused by several factors. Our cases show that the evaluation of fluoride levels in biological material is difficult, as dietary intake, e.g., in drinking water, may complicate acute or chronic occupational exposure.
Urinary biomarkers monitoring for experimental fluoride nephrotoxicity
An excess of sodium fluoride (135 mg F/kg body weight) was given in a single oral dose to male Wistar rats. Effects were investigated of fluoride-induced acute kidney intoxication on the time-dependent variations of urine volume. Also, of urinary fluoride ion (F-), alpha-glutathione-S-transferase (alpha-GST), N-acetyl-beta-D-glucosaminidase (NAG), and creatinine (CR) concentrations.
Combined effects of fluoride and cadmium on liver and kidney function in male rats
It has been shown that cadmium and fluoride may both have adverse effects on liver and kidney functions, but most studies focus on a single agent. In this study, we observed the effects of cadmium and fluoride on liver and kidney functions using a rat model. Total of 24 Sprague–Dawley
Introduction The history of anesthesia is a relatively recent one; if one begins with the analgesia dentist, Horace Wells, who discovered the used nitrous oxide during a dental extraction in the early 1800s. The first public showing of anesthesia occurred in October 1846, when ether was used to prevent pain during surgery
The Influence of fluoride on chronic kidney disease of uncertain aetiology (CKDu) in Sri Lanka.
Fluoride is an element that is widely distributed in the environment. The involvement of fluoride in pathogenesis of Chronic Kidney Disease of uncertain aetiology (CKDu) in Sri Lanka is a much-debated topic. This study aimed to investigate the fluoride concentration in drinking water in CKDu affected areas in Sri Lanka
High fluoride concentrations in the serum and bone of patients with chronic renal failure
The aim was to study the effect of ingested fluoride in patients with chronic renal failure (CRF). Serum fluoride concentrations were measured in 104 subjects, who formed three groups: nondialyzed CRF, dialyzed CRF, and a control group. The iliac bone fluoride was measured in 20 subjects. Serum, urine and water
Related Studies :