Abstract
The biological effects of fluoride were investigated on rats fed pure spring water (natural F- concentration = 0.2 ppm) or spring water enriched with NaF to result 0.8, 1.1 or 2.2 ppm F- during 180 days. The main effects of fluoride have been:
1. Electrocardiographic recordings showed a significant reduction of the electrical systole (QTc).
2. Body weight gain was unaffected by the treatment.
3. Bivalent cations (Ca2+, Mg2+ and Zn2+) were importantly reduced in adrenals, ventricular myocardium, and bone.
4. Na+ concentration was strikingly increased in aorta, lung, and joint of treated animals.
5. In testis, we observed Ca2+ and Na+ retention.
6. Zinc ions were depleted in most tissues, except kidney and submandibular salivary gland.
Our results revealed that chronic administration of fluoridated water does influence systemic biochemical homeostasis in rats, without evoking any overt sign of fluorosis. Moreover, the definition of a “safe” concentration of F- in public w [abstract cut short]
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Fluorosis in Aden
The cases to be described here occurred in the Aden Protectorate where for the last 12 years mass screening of the chest to exclude pulmonary tuberculosis has been carried out. The patients had all drunk the brackish water from the wells, and the analysis of the water from a well
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Fluoride versus sulfur oxides in air pollution.
In reviewing the effects of the 2 pollutants on vegetation and domestic animals there can be no doubt that airborne F-- is far more harmful than sulfur oxides. F-- reaches the blood stream both through inhalation and by ingestion with contaminated food. In plants the translocation of F-- throughout the
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Effect of fluoride on enzymes from serum, liver, kidney, skeletal and heart muscles of mice.
White mice maintained on water containing 100 ppm NaF showed changes in the enzyme level in serum, liver, kidney, heart and skeletal muscles. Enzymes studies were alkaline phosphatase (ALP), acid phosphatase (AcP), glutamate-oxalacetate transaminase (GOT), glutamate-pyruvate transaminase (GPT), lactic dehydrogenase (LDH), isocitric dehydrogenase (ICDH) and cholinesterase (CE). AcP was markedly
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Review of the Bartlett-Cameron survey: a ten year fluoride study.
Analysis of the data produced the following conclusions: 1. As was expected, dental fluorosis was significantly greater in Bartlett than in Cameron (all of the participants born and in continuous residence in Bartlett during the tooth formative period exhibited positive evidence of dental fluorosis). 2. The incidence of cardiovascular disease was higher
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Clinical and hygienic evaluation of the combined effect of vibration and fluoride in humans
By L. Ya. Tartatovskaya, G.N. Samokhvalova, A.G. Antropov Medical Science Centre of Prophylactics and Protection of the Health Workers in Industrial Enterprises, Ekaterinburg, Russia. The study of the combined action of vibration and intense noise, muscular loads and cooling has made it possible to assess the probability of the development of vibration
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Fluoride & Osteoarthritis
While the osteoarthritic effects that occurred from fluoride exposure were once considered to be limited to those with skeletal fluorosis, recent research shows that fluoride can cause osteoarthritis in the absence of traditionally defined fluorosis. Conventional methods used for detecting skeletal fluorosis, therefore, will fail to detect the full range of people suffering from fluoride-induced osteoarthritis.
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