Fluoride concentrations in 42 urinary calculi were determined using a microdiffusion procedure in conjunction with a fluoride sensitive electrode. Mean values of 56, 230 and 1112 ng./mg. fluoride were obtained for uric acid, calcium oxalate monohydrate and apatite/struvite stones, respectively. Fluoride concentration was found to be related to calcium oxalate dihydrate levels as well as to apatite content. It is suggested that the former has zeolithic properties which might trap fluoride while formation and growth of the latter appears to be enhanced by elevated urinary fluoride levels.
Serum and urine fluoride levels in populations of high environmental fluoride exposure with endemic CKDu: a case-control study from Sri Lanka.
Chronic kidney disease of uncertain etiology (CKDu) is a common health issue among farming communities in the dry zone of Sri Lanka where groundwater fluoride is known to be higher than recommended levels. Excessive environmental ingestion of fluoride is widely considered as a possible factor for the onset of CKDu.
Urinary fluoride as a monitoring tool for assessing successful intervention in the provision of safe drinking water supply in five fluoride-affected villages in Dhar district, Madhya Pradesh, India
Endemic fluorosis was detected in 31 villages in the Dhar district of Madhya Pradesh, Central India. Out of the 109 drinking water sources that were analyzed, about 67 % were found to contain high concentration of fluoride above the permissible level of 1.0 mg/l. Dental fluorosis among the primary school children in
[Effects of endoplasmic reticulum stress-induced apoptosis in thyroid injury caused by fluoride in rat].
Objective: To explore the effects of endoplasmic reticulum stress-induced apoptosis in thyroid injury of rats caused by excessive fluoride intake. Methods: All 40 Wistar rats were randomly divided into four groups, control group, low fluoride group, medium fluoride group and high fluoride group. The rats in control group were fed with
Urinary fluoride excretion in Jamaica in relation to fluoridated salt.
The purpose of this study was to compare the urinary fluoride levels in subtropical Jamaica just before the beginning of salt fluoridation (250 mg/kg salt) in 1987 and again 20 months later. Four age groups were studied in three locations with low to intermediate fluoride concentrations in the drinking water.
Fluoride exposure, dopamine relative gene polymorphism and intelligence: A cross-sectional study in China.
Highlights Urine fluoride was inversely associated with IQ. IQ of children with high-activity MAOA genotype was lower than IQ of those with low-activity or female heterozygote genotype. DAT1 and MAOA gene polymorphism modify the effects of UF on IQ. UF, ANKK1, COMT and MAOA have a high-dimensional interaction on
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