Abstract
Urinary tract calculi obtained from 25 patients residing in an endemic fluorotic area revealed a significantly higher fluoride content compared to calculi from 25 persons from a nonendemic area. However the difference in their calcium and phosphate content was not significant. Twenty-four hour urinary fluoride excretion was significantly higher in 10 fluorotic patients than in 10 controls. The incidence of urinary tract calculi was elevated in most of the fluorotic districts of Punjab.
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Determination of fluoride ions in urinary stones by ion chromatography.
A method of the ion chromatographic determination of fluoride ions in urinary stones has been developed. Sample preparation of solid mineral-organic samples includes dissolution in concentrated hydrochloric acid, dilution with deionized water, and the elimination of excess calcium and magnesium cations by adding a KU-2 sulfo cation exchanger in the
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[Fundamental and applied studies on transport and metabolism of electrolytes and glucose--aim to contact with molecular biology]
The authors' research focuses on polyuria, natriuresis, glucosuria, glycemia, and renal calcification in occupational lead poisoning and endemic fluorosis. Changes in electrolyte mobilization and in glucose metabolism and transport following the administration of lead compounds or fluoride were examined to elucidate these mechanisms. The results suggest fundamental approaches to the
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Association between Fluoride Concentration in Public Water Supplies and Beneficial and Adverse Health Outcomes in England: An Ecological Study.
The following abstract was presented by co-author Tony Fletcher at the August 2018 Annual Conference of the International Society for Environmental Epidemiology (ISEE) in Ottawa, Canada. The protective effect of community water fluoridation (CWF) on caries is established, but secular changes may modify its impact. Relationships with adverse health outcomes have
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Sodium fluoride increases intracellular calcium in rat renal epithelial cell line NRK-52E
In our previous experiment using rats, fluoride was reported to cause renal calcification, whose mechanism was deduced to be due to an increase in parathyroid hormone (PTH) secretion. However fluoride-induced renal calcification that was independent of PTH has not been understood well in the nephron of fluoride-treated animals. Thus, we
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Correlative study of fluoride content in urine, serum and urinary calculi
Fluoride content was measured in 100 urinary stones retrieved by open surgery of stone formers admitted at PGIMS Rohtak and their respective urine and serum and compared with those of healthy individuals. The concentration of fluoride was also measured in the sources of drinking water of these stone formers. The
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