Abstract

SUMMARY: Sixty-five operations workers (all males) in an electrolytic aluminum production facility were divided into two groups. The first group of 37 was employed for more than 5 years, and the second group of 28 for 5 years or less. These men had no history of liver, kidney, or immune-related disease. X-ray tests indicated that they were not suffering from occupational fluorosis (according to the standards of GB3234-82). For controls, 52 males from the service departments with no history of exposure to fluoride were used as controls. Neurobehavioral function of the long exposure group measured by the neurobehavioral core test battery (NCTB) revealed, with the exception of the Benton visual retention measurement, diminished performance for every testing index as compared to the controls. Even the scores for emotional state of the short exposure group were markedly lower than for the control. By relating these test results to fluoride exposure, our study demonstrated various effects of occupational fluoride exposure on the central nervous system, thereby providing early warning indicators that can be used to protect the health of workers who have occupational contact with fluoride.

• Related Studies :

  • Chronic Fluoride Exposure and the Risk of Autism Spectrum Disorder.

    The continuous rise of autism spectrum disorder (ASD) prevalent in the past few decades is causing an increase in public health and socioeconomic concern. A consensus suggests the involvement of both genetic and environmental factors in the ASD etiopathogenesis. Fluoride (F) is rarely recognized among the environmental risk factors of

  • Effects of high fluoride level on neonatal neurobehavioral development

    The effects of excessive fluoride intake during pregnancy on neonatal neurobehavioral development and the neurodevelopment toxicity of fluoride were evaluated. Ninety-one normal neonates delivered at the department of obstetrics and gynecology in five hospitals of Zhaozhou County, Heilongjiang Province, China were randomly selected from December 2002 to January 2003. The

  • Psychopharmacology of fluoride: a review

    Although the blood-brain barrier is relatively impermeable to fluoride, it does not pose an absolute barrier and fluoride has the ability to enter the brain. The literature was examined to assess the quality of the evidence for cerebral impairment occurring due to exposure to fluoride from therapeutic or environmental sources.

  • Characterization of nervous system intoxication in occupational fluorosis

    Neurological symptomatology in the form of the syndrome of vegetative-vascular dysfunction, or the asthenovegetative syndrome with polyneuritic (sensory and vegetative) disorders was detected in 78.8 per cent of patients with occupational fluorosis in preosteal and osteal stages. Clinical and physiological investigations of the nervous system (psycho-physiological procedures, electroencephalography, chronaximetry) showed

  • Assessment of pain in fluorosis-induced rats

    Toxic effects of fluoride (F) are now well known. If chronically absorbed, F induces dental and skeletal abnormalities, neurotoxical effects, especially when F levels are higher than 4 ppm and/or when cells are at an early stage of their development. Moreover a spontaneous acute pain syndrome of lower extremities is frequently

• Related FAN Content :

  • NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects

    The NRC's analysis on fluoride and the brain.

  • Fluoride: Developmental Neurotoxicity.

    Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching

  • Fluoride's Effect on Fetal Brain

    The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts

  • Fluoride Affects Learning & Memory in Animals

    An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out

  • Fluoride & IQ: 67 Studies

    As of May 2020, a total of 75 studies have investigated the relationship between fluoride and human intelligence. Of these investigations, 67 studies have found that elevated fluoride exposure is associated with reduced IQ in humans, while over 60 animal studies have found that fluoride exposure impairs the learning and/or