To study the influence on children’s growth by long-term high fluoride exposure.
Case group was selected in high fluoride areas and control group was selected in non-high fluoride areas. The difference of children’s growth levels were analyzed between 2 groups.
The IQ of case group was significantly lower than that of control group (t = 2.621, P<0.01) and it was negatively correlative with the concentration of children’s urinary fluoride in a certain extent (r = -0.119, P<0.05). Children’s heights and weights of case group were significantly lower than those of control group (t = 2.621, P<0.01 u = 3.515 P < 0.01).
Long-term fluoride exposure can affect children’s growth and development. In order to protect children’s health measures of prevention and treatment should be adopted.
Fluoride exposure, dopamine relative gene polymorphism and intelligence: A cross-sectional study in China.
Highlights Urine fluoride was inversely associated with IQ. IQ of children with high-activity MAOA genotype was lower than IQ of those with low-activity or female heterozygote genotype. DAT1 and MAOA gene polymorphism modify the effects of UF on IQ. UF, ANKK1, COMT and MAOA have a high-dimensional interaction on
OP V – 2 Prenatal fluoride exposure and neurobehavior among children 1–3 years of age in Mexico
Background/aim Recent studies report an inverse association between fluoride (F) exposure and IQ in children, but few included individual measures of exposure or assessed associations with prenatal exposure using a prospective study design. Methods This study utilised the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) birth cohort and archived pregnancy samples
Effect of coal-burning endemic fluorosis on children's physical development and intellectual level
Objective To investigate the effect of coal-burning endemic fluorosis on children's physical development and intellectual level so as to provide data support for the protection of children's healthy growth in fluorosis areas. Methods Ninety children with coal-burning endemic fluorosis were selected for the study, which were divided into heavy fluorosis area group, middle
Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 6–12 Years of Age in Mexico
Background: Some evidence suggests that fluoride may be neurotoxic to children. Few of the epidemiologic studies have been longitudinal, had individual measures of fluoride exposure, addressed the impact of prenatal exposures or involved more than 100 participants. OBJECTIVE: Our aim was to estimate the association of prenatal exposure to fluoride with
The relationships between thyroid-stimulating hormone and/or dopamine levels in peripheral blood and IQ in children with different urinary iodine concentrations.
Highlights TSH is not related IQ in children with different urinary iodine concentrations. Dopamine in plasma is unrelated to IQ in children with adequate or excessive iodine. Dopamine has positive correlation with intelligence in iodine deficiency group. The interaction between dopamine in plasma and TSH is not related to
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As of February 2021, a total of 76 studies have investigated the relationship between fluoride and human intelligence. Of these investigations, 68 studies have found that elevated fluoride exposure is associated with reduced IQ in humans, while over 60 animal studies have found that fluoride exposure impairs the learning and/or
Fluoride Affects Learning & Memory in Animals
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Fluoridated Water Causes Severe Dental Fluorosis in Children with Diabetes Insipidus
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Mayo Clinic: Fluoridation & Bone Disease in Renal Patients
The available evidence suggests that some patients wtih long-term renal failure are being affected by drinking water with as little as 2 ppm fluoride. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers. The finding of adverse effects in patients drinking water with 2 ppm of fluoride suggests that a few similar cases may be found in patients imbibing 1 ppm, especially if large volumes are consumed, or in heavy tea drinkers and if fluoride is indeed the cause. It would seem prudent, therefore, to monitor the fluoride intake of patients with renal failure living in high fluoride areas.
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