The fluoride content of drinking water is directly correlated with the serum and saliva fluoride. Serum fluoride levels are also directly related to those of saliva, but not to urinary fluoride.
These interrelations are so close that a mathematical formula can be devised for the calculation of fluoride in body fluids. For instance, a sample of saliva may serve for the quantification of serum fluoride. Whereas these interrelations are observed in general population groups they do not always apply to individuals.
Biomarkers for the Assessment of Fluoride Exposure in Children.
Due to practical difficulties in quantifying fluoride exposure, the ability of various biomarkers to predict exposure has been investigated previously. However, the results are inadequate for validation of their application and usefulness. This study aimed to investigate the association between contemporary/recent biomarkers of fluoride exposure and total daily fluoride intake
Linear regression approach for predicting fluoride concentrations in maternal serum, urine and cord blood of pregnant women consuming fluoride containing drinking water.
Purpose The most common source of fluoride is from drinking water. Research comparing fluoride levels in maternal and cord blood have proved that fluoride crosses the placenta. But these results have not been correlated with the source of fluoride. Objective Firstly, to assess and compare the fluoride concentrations in urine, serum and cord
Skeletal Fluorosis: An Unusual Manifestation of Computer Cleaner Inhalant Abuse.
Skeletal fluorosis is a metabolic bone disease caused by accumulation of fluoride and is generally associated with chronic exposure to fluoride-contaminated groundwater, a phenomenon endemic to developing countries. Whereas elevated water fluoride concentrations do not constitute a public health issue in the United States, emergence of skeletal fluorosis as a
Cognitive impairment and risk factors in elderly people living in fluorosis areas in China
Residents living in fluorosis areas generally experienced long-term exposure to excessive fluoride in drinking water. The adverse effects of high fluoride levels on the nervous system have been studied; however, the effect of fluoride exposure on cognitive functions of elderly people in fluorosis areas is rarely reported. This study was
Studies of relationships between the polymorphism of COMT gene and plasma proteomic profiling and children’s intelligence in high fluoride areas
Part I – Effect of high F drinking water on children’s IQ Objective: To investigate the relationships among the children’s serum F, urine F, thyroid hormone levels and children’s IQ in the high fluoride areas. Methods: We collected the samples of the drinking water, urine and blood and measured the F concentrations,
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