Abstract
The aim of this work was to evaluate the impact of fluoride exposure on the prevalence of dental caries and the intellectual ability of children.
Method: In this cross-sectional study, 161 children from 9 to 10 years of age were evaluated. The concentration of fluoride in drinking water and urine was analyzed individually. Oral health status regarding dental caries and dental fluorosis was assessed. The intellectualability of children was evaluated through the Raven’s Colored Progressive Matrices. In addition, variables such as diet, oral hygiene, body mass index, and socioeconomic status were included.
Results: There was a negative relationship between the DMFT index and the level of dental fluorosis. In the logistic regression analysis, a water fluoride exposure above 1.0 mg/L showed less risk of dental caries (OR = 0.41; p=0.025). Parental education level lower than high school raised significantly the risk of dental caries (OR = 2.81; p=0.036). No relationship was found between intellectual ability and fluoride exposure variables such as, dental fluorosis, levels of fluoride in drinking water and urine, and exposure dose.
Conclusion: The results suggest that exposure to fluoride reduces the prevalence of dental caries, but no association was found to the intelligence of children.
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Systematic review of epidemiological and toxicological evidence on health effects of fluoride in drinking water.
Introduction Fluoride is a naturally occurring substance that is also added to drinking water, dental hygiene products, and food supplements for preventing dental caries. Concerns have been raised about several other potential health risks of fluoride. Objective To conduct a robust synthesis of evidence regarding human health risks due to exposure to fluoride
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Prenatal exposure to fluoride and neuropsychological development in early childhood: 1-to 4 years old children.
Highlights Maternal fluoride levels were associated with better cognitive scores in childhood. The neuropsychological association is gender dependent; only seen in boys. Positive associations do not disappear after adjustment by different covariates. A potential positive neuropsychological association at low fluoride levels cannot be excluded. Background Cross-sectional and prospective studies have provided
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Arsenic and fluoride co-exposure through drinking water and their impacts on intelligence and oxidative stress among rural school-aged children of Lahore and Kasur districts, Pakistan.
Arsenic (As), and fluoride (F-) are potent contaminants with established carcinogenic and non-carcinogenic impacts on the exposed populations globally. Despite elevated groundwater As and F- levels being reported from various regions of Pakistan no biomonitoring study has been reported yet to address the co-exposure impact of As and F- among
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Effects of High-Water Fluoride Exposure on IQ Levels in School-Age Children: A Cross-Sectional Study in Jiangsu, China
This cross-sectional research aimed to investigate the potential effects of elevated fluoride levels in drinking water on children’s intelligence quotient (IQ). A total of 721 children from rural Jiangsu, China, were included in the study and divided into two groups based on the fluoride concentration in their drinking water: a
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Low-moderate fluoride exposure and intelligence among Chinese school-aged children: Role of circulating mtDNA content.
Highlights First epidemiologic study links mtDNA content with fluoride-caused lower IQ scores. MtDNA content was positively correlated to odds of having excellent intelligence. MtDNA content mediated relations of fluoride to reduced odds of excellent intelligence in girls. Mitochondrial DNA (mtDNA) content alterations are potential mediators of neuronal disorders. However, what
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Fluoride & IQ: 76 Studies
Note: See the Updated list of fluoride IQ studies at https://fluoridealert.org/researchers/fluoride-iq-studies/the-fluoride-iq-studies/ • As of July 18, 2022, a total of 85 human studies have investigated the relationship between fluoride and human intelligence. • Of these investigations, 76 studies have reported that elevated fluoride exposure is associated with reduced IQ in humans. • The studies
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Fluoride Affects Learning & Memory in Animals
An association between elevated fluoride exposure and reduced intelligence has now been observed in 65 IQ studies. Although a link between fluoride and intelligence might initially seem surprising or random, it is actually consistent with a large body of animal research. This animal research includes the following 45 studies (out
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Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
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Fluoride's Effect on Fetal Brain
The human placenta does not prevent the passage of fluoride from a pregnant mother's bloodstream to the fetus. As a result, a fetus can be harmed by fluoride ingested pregnancy. Based on research from China, the fetal brain is one of the organs susceptible to fluoride poisoning. As highlighted by the excerpts
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NRC (2006): Fluoride's Neurotoxicity and Neurobehavioral Effects
The NRC's analysis on fluoride and the brain.
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