Abstract
The aim of this work was to evaluate the impact of fluoride exposure on the prevalence of dental caries and the intellectual ability of children.
Method: In this cross-sectional study, 161 children from 9 to 10 years of age were evaluated. The concentration of fluoride in drinking water and urine was analyzed individually. Oral health status regarding dental caries and dental fluorosis was assessed. The intellectualability of children was evaluated through the Raven’s Colored Progressive Matrices. In addition, variables such as diet, oral hygiene, body mass index, and socioeconomic status were included.
Results: There was a negative relationship between the DMFT index and the level of dental fluorosis. In the logistic regression analysis, a water fluoride exposure above 1.0 mg/L showed less risk of dental caries (OR = 0.41; p=0.025). Parental education level lower than high school raised significantly the risk of dental caries (OR = 2.81; p=0.036). No relationship was found between intellectual ability and fluoride exposure variables such as, dental fluorosis, levels of fluoride in drinking water and urine, and exposure dose.
Conclusion: The results suggest that exposure to fluoride reduces the prevalence of dental caries, but no association was found to the intelligence of children.
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Fluoride exposure and intelligence in school-age children: evidence from different windows of exposure susceptibility.
BACKGROUND The intellectual loss induced by fluoride exposure has been extensively studied, but the association between fluoride exposure in different susceptibility windows and children’s intelligence is rarely reported. Hence, we conducted a cross-sectional study to explore the association between fluoride exposure in prenatal and childhood periods and intelligence quotient (IQ). Methods We recruited
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Associations Between Prenatal Fluoride Exposure and Performance IQ in Canadian Preschool Aged Children: A Multilevel Modeling Approach.
BACKGROUND AND AIM: Prenatal fluoride exposure is associated with reduced IQ in children, especially Performance IQ (PIQ; nonverbal intelligence), but studies have not accounted for hierarchical clustering. We examined the association between sex-specific prenatal fluoride exposure and PIQ using multilevel modeling (MLM) to account for nesting of 448 mother-child pairs
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OP V – 2 Prenatal fluoride exposure and neurobehavior among children 1–3 years of age in Mexico
Background/aim Recent studies report an inverse association between fluoride (F) exposure and IQ in children, but few included individual measures of exposure or assessed associations with prenatal exposure using a prospective study design. Methods This study utilised the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) birth cohort and archived pregnancy samples
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Critical Windows of Fluoride Neurotoxicity in Canadian Children.
Highlights The association between fluoride and performance IQ (PIQ) significantly differed across prenatal, infancy, and childhood exposure windows collapsing across child sex (p = .001). The strongest association between fluoride and PIQ was during the prenatal window, B = -2.36, 95% CI: -3.63, -1.08; the association was also significant
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The cholinergic system, intelligence, and dental fluorosis in school-aged children with low-to-moderate fluoride exposure.
Highlights Low-to-moderate fluoride was associated with alterations of cholinergic system. The prevalence of dental fluorosis (DF) was related to cholinergic system. AChE was negatively associated with children’s intelligence quotient (IQ). AChE mediates association of fluoride with DF prevalence and lower odds of IQ > 120. DF and IQ were
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Fluoride Affects Learning & Memory in Animals
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Fluoride's Direct Effects on Brain: Animal Studies
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