Abstract

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  • Studies of the effect of salt iodization on endemic goiter in Taiwan. IV. A survey of drinking-water in relation to endemic goiter.

    No abstract available

  • [Effect of different fluoride and iodine concentration in drinking water on children's dental fluorosis and thyroid function].

    Objective: To investigate the effect of different concentrations of fluoride and iodine in drinking water on children's dental fluorosis and thyroid function. Methods: According to different concentration of fluoride and iodine in drinking water, four villages in two counties of Henan province were classified as high fluoride and iodine, high fluoride,

  • [Expressions of iNOS and VEGF mRNAs in thyroid gland of rat with goiter induced by fluoride].

    To investigate the mechanism of goiter caused by fluoride, goiter model of SD rats was produced by administering sodium fluoride in drinking water. Histological section of thyroid gland was made, and inducible nitric oxide synthase (iNOS) and vessel endothelial growth factor (VEGF) were determined by RT-PCR. Results showed that the

  • Endemic goiter associated with high iodine intake in primary school children in the Saharawi Arab Democratic Republic.

    The high prevalence of goiter in Saharan children visiting Asturias in the summer prompted us to study the problem in greater depth. Neck palpation was performed in a sample of 570 school children from the Saharawi Arab Democratic Republic. Weight, height, T4, thyroid-stimulating hormone and anti-thyroperoxidase antibodies in capillary blood were

  • Role of nitric oxide and vascular endothelial growth factor in fluoride-induced goitrogenesis in rats

    Endemic fluorosis is a serious problem in public health. Previous studies have indicated that patients with thyroid goiters usually live in fluoride-affected areas. However, the mechanism of goitrogenesis caused independently by fluoride is still unclear. The principle objective of this study was to investigate the possible roles of nitric oxide

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  • The Relationship Between Fluoride Exposure & Goitre in South Africa

    As a general rule simple goitre, irrespective of the cause, can be very, or fairly, satisfactorily combated by an adequate increase in man's daily iodine intake, except when the enlargement of the gland is due to the ingestion of excessive amounts of fluorine. The only correct solution to fluorine-induced endemic goitre is the removal of this element from the drinking water.

  • Fluoride, Water Hardness, and Endemic Goitre

    Variations in goitre prevalence were found to correlate closely with the fluoride content (p=0-74; P<0-01) and with the hardness (p=0.77; P<0-01) of the water in each village. The effects of fluoride and water hardness seem to be independent.

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    Goitre (aka goiter) is an enlargement of the thyroid gland that in some cases can produce visible swelling in the neck. The main cause of goitre is iodine deficiency. Goitre can also be caused by other things, including hypothyroidism and substances that cause goitre (goitrogens). Since as far back as the

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    The distribution of endemic goitre in the Punjab and in England is related to the geological distribution of fluorine and to the distribution of human dental fluorosis (mottled enamel). Inquiry showed the presence of dental fluorosis among school-children in two areas of Somerset where two previous observers had recorded a high incidence of goitre, and the absence of dental fluorosis in an adjoining area selected as control where endemic goitre was absent.

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