SUMMARY: As part of our investigation of fluoride toxicity effects in a group of 80
Swiss albino adult male mice, we examined the mitigating effects of black tea extract
(BTE) on the F-induced enzymatic and non-enzymatic parameters of oxidative stress
in the cerebral hemisphere (CH), cerebellum (CB), and medulla oblongata (MO) of the brains of these mice. Oral administration of 6 and 12 mg NaF/kg bw/day to the mice for 30 days resulted in a significant increase in level of lipid peroxidation (LPO) and dehydroascorbic (DAA) acid as well as a decrease in glutathione (GSH), total
ascorbic acid (TAA), and reduced ascorbic acid. In addition, the activities of the
enzymatic antioxidants catalase (CAT), superoxide dismutase (SOD), glutathione
reductase (GSH-Pr), and glutathione peroxidase (GSH-Px) as well as cholinesterase
(ChE) also decreased. No significant recovery in any of these parameters was
observed upon withdrawal of the NaF treatment for 30 days. However, administration of BTE along with the NaF during the experiment resulted in significant mitigation of all the NaF-induced effects that were examined.
Amelioration by black tea of sodium fluoride-induced changes in protein content of cerebral hemisphere, cerebellum and medulla oblongata in brain region of mice.
Oral administration of sodium fluoride (NaF, 6 and 12 mg/kg body weight/day) to Swiss strain male albino mice for 30 days caused significant dose-dependant reduction in the content of acidic, basic, neutral, and total protein in cerebral hemisphere, cerebellum and medulla oblongata region of brain. After 30 days of NaF
Mitigation of sodium fluoride induced toxicity in mice brain by black tea infusion.
SUMMARY: In an extension of previous work on fluoride (F) toxicity in a group of 80 Swiss albino mice, the mitigating effects of polyphenols in black tea on the F-induced increase in glycogen, cholesterol, and total lipids in the cerebral hemisphere (CH), cerebellum (CB), and medulla oblongata (MO) regions of
Serum fluoride concentrations in renal insufficiency
In an area with non-fluoridated water (F content, 0.061 ppm), serum fluoride concentrations as measured with an ion specific electrode were as follows: controls (N = 13), 0.0127 ppm + 0.0057 (mean + SD); renal insufficiency (N = 10), 0.0452 ppm + 0.0151; chronic hemodialysis (N = 11), 0.0424 +
Fluoride intake from the consumption of refreshment drinks and natural juices.
Highlights Soft-drinks and juices (65) were analyzed by potentiometry. Tea-based beverages had the highest fluoride content. Fluoride intake does not lead to a risk in adult health. Consumption of these beverages by children should be moderated. Fluoride plays an important role in the prevention of dental decay and in the reduction
Brick tea fluoride as a main source of adult fluorosis
An epidemiological survey was conducted in Naqu County, Tibet in September 2001 to investigate the manifestations of fluorosis in adults caused by the habitual consumption of brick tea. Profiles were obtained for the total daily fluoride intake, environmental fluoride levels and average urinary fluoride concentration, and a physical examination and a
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Fluoride Content of Tea
Tea, particularly tea drinks made with lower quality older leaves, contain high levels of fluoride. Because of these high levels, research has found that individuals who drink large amounts of tea can develop skeletal fluorosis -- a painful bone disease caused by excessive fluoride intake. Since skeletal fluorosis is often misdiagnosed by
Fluoride: Developmental Neurotoxicity.
Developmental Neurotoxicity There has been a tremendous amount of research done on the association of exposure to fluoride with developmental neurotoxicity. There are over 60 studies reporting reduced IQ in children and several on the impaired learning/memory in animals. And there are studies which link fluoride to Attention Deficit Hyperactivity Disorder. Teaching
Fluoride's Direct Effects on Brain: Animal Studies
The possibility that fluoride ingestion may impair intelligence and other indices of neurological function is supported by a vast body of animal research, including over 40 studies that have investigated fluoride's effects on brain quality in animals. As discussed by the National Research Council, the studies have consistently demonstrated that fluoride, at widely varying concentrations, is toxic to the brain.
The Lancet: Fluoride Studies in a Patient with Arthritis
It is possible that fluoride intake from tea may be sufficient to cause fluorosis, and I report here a case which gives some evidence for this.
Exposure Pathways Linked to Skeletal Fluorosis
Excessive fluoride exposure from any source -- and from all sources combined -- can cause skeletal fluorosis. Some exposure pathways , however, have been specifically identified as placing individuals at risk of skeletal fluorosis. These exposure pathways include: Fluoridated Water for Kidney Patients Excessive Tea Consumption High-Fluoride Well Water Industrial Fluoride Exposure Fluorinated Pharmaceuticals (Voriconazole
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