Transplacental passage of fluorides was studied in 25 randomly selected neonates. Blood samples collected simultaneously from the mother and the umbilical cord showed that average fluoride concentration in the cord blood was 60% of that in mother’s blood. When concentration in the mother’s blood exceeded 0.4 ppm, the placenta acted as a selective barrier.
Proposed mechanism for understanding the dose- and time-dependency of the effects of fluoride in the liver.
Fluoride (F) can induce changes in the expression of several liver proteins.It is suggested that these changes are dose- and time-dependent. The objective of this study was to analyze the effect of different F concentrations and exposure times to this ion on the pattern of protein expression in the liver
Fluoride levels and biochemical assessments in cattle accidentally exposed to hydrofluoric acid in Korea.
On September 27, 2012, an explosion from hydrofluoric acid occurred in Gumi city of Gyeongbuk province, Republic of Korea, exposing livestock animals nearby to Hydrofluoric acid (HF). This study aimed at evaluating the HF exposure among cattle raised near the accident site by determining the fluoride ion (F?1) levels and
Fluoride level in plasma blood and urine of first-trimester pregnant women living in a province.
The study was aimed to determine the fluoride level in blood and urine of 154 first-trimester pregnant women among 7 public hospitals of a province. The concentration of plasma-blood fluoride was not determined in all subjects. For concentration of urine fluoride concentration, 77 cases (50.6%) had low fluoride level (less
The association between fluoride in water and blood pressure in children and adolescents.
Background The objective of this study was to determine the association between water and plasma fluoride and blood pressure (BP) among children and adolescents. Methods Our study population was individuals of 8–18 years in the 2013–2016 National Health and Nutrition Examination Survey. We performed a multivariable linear and logistic regression analysis to examine
Plasma and water fluoride levels and hyperuricemia among adolescents: A cross-sectional study of a nationally representative sample of the United States for 2013–2016.
Highlights Relatively low levels of fluoride exposure in US adolescents but with wide ranges. Dose-dependent increase in prevalence of hyperuricemia with increasing fluoride levels. Significant associations between plasma and water fluoride and hyperuricemia. A positive relationship between water and plasma fluoride concentrations. Potential role of chronic fluoride exposure in
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