Fluoride Action Network

Abstract

Contamination of arsenic and fluoride in drinking water reservoirs is a serious health issue in the Sibi district, Balochistan, Pakistan. The contamination has already been affecting a large population of the district. Dental fluorosis and dermatitis are the most common reported illnesses in the area. This study focused on the evaluation of the root causes and pathway by which it reached to the body. Questioner analysis, simple examination, and pictorial representation were used to study the prevalence of diseases caused by As and F. People of the Sibi district were found to consume both surface and groundwater, which were highly contaminated with arsenic and fluoride. The saturation index, ranging from 1 to 7, showed high enrichment of contaminants in both types of water. Geochemical calculations and the sodium absorption ratio were evaluated. High values of the saturation index of different salts showed high saturation of salts in water. The principal component analysis grouped the data into three clusters, showing that the surface water has no resemblance with the control water. High degree of contamination was observed for most of the samples, whereas, some samples of ground water were closed to the control group; a group of samples within WHO limits. The correlation studies and other calculations also revealed that the F and As reached lethal limits in the drinking water and thus caused severe health damage to the local area population. The diseases found in the area are fluorosis, keratosis, dermatitis, and melanosis.

*Original abstract online at https://link.springer.com/article/10.1007%2Fs11356-020-10575-9

References

Ahamed S, Sengupta MK, Mukherjee A, Hossain MA, Das B, Nayak B, Chatterjee G (2006) Arsenic groundwater contamination and its health effects in the state of Uttar Pradesh (UP) in upper and middle Ganga plain, India: a severe danger. Sci Total Environ 370(2):310–322

CAS  Google Scholar

Baig JA, Kazi TG, Arain MB, Shah AQ, Sarfraz RA, Afridi HI, Kandhro GA, Jamali MK, Khan S (2009) Arsenic fractionation in sediments of different origins using BCR sequential and single extraction methods. J Hazard Mater 167(1):745–751

CAS  Google Scholar Brahman KD, Kazi TG, Afridi HI, Baig JA, Arain SS, Talpur FN, Kazi AG, Ali J, Panhwar AH, Arain MB (2016) Exposure of children to arsenic in drinking water in the Tharparkar region of Sindh, Pakistan. Sci Total Environ 544:653–660

CAS  Google Scholar

Bulka CM, Jones RM, Turyk ME, Stayner LT, Argos M (2016) Arsenic in drinking water and prostate cancer in Illinois counties: an ecologic study. Environ Res 148:450–456

CAS  Google Scholar

Cao J, Zhao Y, Liu J, Xirao R, Danzeng S (2000) Fluoride concentrations of water sources in Tibet. Fluoride 33(4):205–209

CAS  Google Scholar

Cebrian ME, Albores A, Aguilar M, Blakely E (1983) Chronic arsenic poisoning in the north of Mexico. Hum Toxicol 2(1):121–133

CAS  Google Scholar

Chakraborti D (2011) Arsenic: occurrence in groundwater, Encyclopedia of Environmental Health. Elsevier, Burlington, pp 165–180

Google Scholar

Chakraborti D, Chanda CR, Samanta G, Chowdhury UK, Mukherjee SC, Pal AB et al (2000) Fluorosis in Assam, India. Curr Sci 78(12):1421–1423

Google Scholar

Chakraborti D, Mukherjee SC, Pati S, Sengupta MK, Rahman MM, Chowdhury UK, Basu GK (2003) Arsenic groundwater contamination in Middle Ganga Plain, Bihar, India: a future danger? Environ Health Perspect 111(9):1194–1201

CAS  Google Scholar

Chandio TA, Khan MN, Sarwar A (2015) Fluoride estimation and its correlation with other physicochemical parameters in drinking water of some areas of Balochistan, Pakistan. Environ Monit Assess 187(8):531

Google Scholar

Chen CJ, Wang CJ (1990) Ecological correlation between arsenic level in well water and age-adjusted mortality from malignant neoplasms. Cancer Res 50(17):5470–5474

CAS  Google Scholar

Chen CJ, Chuang YC, You SL, Lin TM, Wu HY (1986) A retrospective study on malignant neoplasms of bladder, lung and liver in blackfoot disease endemic area in Taiwan. Br. J. Cancer 53(3):399

CAS  Google Scholar

Chen CJ, Kuo TL, Wu MM (1988) Arsenic and cancers. Lancet 1:414–415

CAS  Google Scholar

Chen CJ, Hsueh YM, Lai MS, Shyu MP, Chen SY, Wu MM, Tai TY (1995) Increased prevalence of hypertension and long-term arsenic exposure. Hypertens. 25(1):53–60

Google Scholar

Chen CJ, Wang SL, Chiou JM, Tseng CH, Chiou HY, Hsueh YM, Lai MS (2007a) Arsenic and diabetes and hypertension in human populations: a review. Toxicol Appl Pharmacol 222(3):298–304

CAS  Google Scholar

Chen K, Jiao JJ, Huang J, Huang R (2007b) Multivariate statistical evaluation of trace elements in groundwater in a coastal area in Shenzhen, China. Environ Pollut 147(3):771–780

CAS  Google ScholarChowdhury UK, Biswas BK, Chowdhury TR, Samanta G, Mandal BK, Basu GC et al (2000) Groundwater arsenic contamination in Bangladesh and West Bengal, India. Environ Health Perspect 108(5):393

CAS  Google Scholar

Dang HS, Jaiswal DD, Somasundaram S (1983) Distribution of arsenic in human tissues and milk. Sci Total Environ 29(1–2):171–175

CAS  Google Scholar

Danielsson Å, Cato I, Carman R, Rahm L (1999) Spatial clustering of metals in the sediments of the Skagerrak/Kattegat. Appl Geochem 14(6):689–706

CAS  Google Scholar

Datta DK, Gupta LP, Subramanian V (2000) Dissolved fluoride in the lower Ganges-Brahmaputra-Meghna river system in the Bengal Basin, Bangladesh. Environ Geol 39(10):1163–1168

CAS  Google Scholar

Engel RR, Hopenhayn-Rich C, Receveur O, Smith AH (1994) Vascular effects of chronic arsenic exposure: a review. Epidemiol Rev 16(2):184–209

CAS  Google Scholar

Farooqi A, Masuda H, Firdous N (2007) Toxic fluoride and arsenic contaminated groundwater in the Lahore and Kasur districts, Punjab, Pakistan and possible contaminant sources. Environ Pollut 145(3):839–849

CAS  Google Scholar

Flanagan SV, Johnston RB, Zheng Y (2012) Arsenic in tube well water in Bangladesh: health and economic impacts and implications for arsenic mitigation. Bull World Health Organ 90(11):839–846

Google Scholar

Gikunju JK, Simiyu KW, Gathura PB, Kyule M, Kanja LW (2002) River water fluoride in Kenya. Fluoride 35(3):193–196

CAS  Google Scholar

Gizaw B (1996) The origin of high bicarbonate and fluoride concentrations in waters of the Main Ethiopian Rift Valley, East African Rift system. J Afr Earth Sci 22(4):391–402

CAS  Google Scholar

Harrison PT (2005) Fluoride in water: a UK perspective. J Fluor Chem 126(11):1448–1456

CAS  Google ScholarHarvey CF, Swartz CH, Badruzzaman ABM, Keon-Blute N, Yu W, Ali MA, Oates PM (2002) Arsenic mobility and groundwater extraction in Bangladesh. Science 298(5598):1602–1606

CAS  Google Scholar

Hasan MA, Ahmed KM, Sracek O, Bhattacharya P, Von Broemssen M, Broms S, Jacks G (2007) Arsenic in shallow groundwater of Bangladesh: investigations from three different physiographic settings. Hydrogeol J 15(8):1507–1522

CAS  Google Scholar

International Agency for Research on Cancer (1980) IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some metals and metallic compounds. World Health Organization, Lyon

Google Scholar

Jacks G, Bhattacharya P, Chaudhary V, Singh KP (2005) Controls on the genesis of some high fluoride groundwaters in India. Appl Geochem 20(2):221–228

CAS  Google Scholar

Kadono T, Inaoka T, Murayama N, Ushijima K, Nagano M, Nakamura S, Ohtsuka R (2002) Skin manifestations of arsenicosis in two villages in Bangladesh. Int J Dermatol 41(12):841–846

Google Scholar

Kahama RW, Kariuki DN, Kariuki HN, Njenga LW (1997) Fluorosis in children and sources of fluoride around Lake Elementaita region of Kenya. Fluoride 30(1):19–25

CAS  Google Scholar

Kazi TG, Arain MB, Jamali MK, Jalbani N, Afridi HI, Sarfraz RA, Baig JA, Shah AQ (2009) Assessment of water quality of polluted lake using multivariate statistical techniques: a case study. Ecotoxicol Environ Saf 72(2):301–309

Kundu N, Panigrahi M, Tripathy S, Munshi S, Powell MA, Hart B (2001) Geochemical appraisal of fluoride contamination of groundwater in the Nayagarh District of Orissa, India. Environ Geol 41(3):451–460

CAS  Google Scholar

Lopez PL, Auque LF, Garces I, Chong W (1999) Geochemical characteristics and pattern of evolution of salmueras superficiales del Salar de Llamara, Chile Brines surface of Salar Llamara, Chile. Geol Mag Chile 26:89–108

CAS  Google Scholar

Mandal BK, Suzuki KT (2002) Arsenic round the world: a review. Talanta 58(1):201–235

CAS  Google Scholar

McCaffrey LP, Willis JP (2001) Distribution of fluoride-rich groundwater in the eastern and Mogwase regions of the Northern and North-West Provinces. Water Research Commission

Meybeck M (1987) Global chemical weathering of surficial rocks estimated from river dissolved loads. Am J Sci 287(5):401–428

CAS  Google Scholar

Mukherjee SC, Saha KC, Pati S, Dutta RN, Rahman MM, Sengupta MK et al (2005) Murshidabad—one of the nine groundwater arsenic-affected districts of West Bengal, India. Part II: dermatological, neurological, and obstetric findings. Clin Toxicol 43(7):835–848

CAS  Google Scholar

Nayak B, Roy MM, Chakraborti D (2009) Dental fluorosis. Clin Toxicol 47(4):355–355

Google Scholar

Rafique T, Naseem S, Bhanger MI, Usmani TH (2008) Fluoride ion contamination in the groundwater of Mithi sub-district, the Thar Desert, Pakistan. Environ Geol 56(2):317–326

CAS  Google Scholar

Rafique T, Naseem S, Usmani TH, Bashir E, Khan FA, Bhanger MI (2009) Geochemical factors controlling the occurrence of high fluoride groundwater in the Nagar Parkar area, Sindh, Pakistan. J Hazard Mater 171(1):424–430

CAS  Google Scholar

Rahman MM, Chowdhury UK, Mukherjee SC, Mondal BK, Paul K, Lodh D et al (2001) Chronic arsenic toxicity in Bangladesh and West Bengal, India—a review and commentary. J Toxicol Clin Toxicol 39(7):683–700

CAS  Google Scholar

Sarma DRR, Rao SLN (1997) Fluoride concentrations in ground waters of Visakhapatnam, India. Bull Environ Contam Toxicol 58(2):241–247

CAS  Google Scholar

Saxena V, Ahmed S (2003) Inferring the chemical parameters for the dissolution of fluoride in groundwater. Environ Geol 43(6):731–736

CAS  Google Scholar

Smith AH, Hopenhayn-Rich C, Bates MN, Goeden HM, Hertz-Picciotto I, Duggan HM, Smith MT (1992) Cancer risks from arsenic in drinking water. Environ Health Perspect 97:259–267

CAS  Google Scholar

Smith AH, Lopipero PA, Bates MN, Steinmaus CM (2002) Arsenic epidemiology and drinking water standards. Science 296(5576):2145–2146

CAS  Google Scholar

Sreedevi PD, Ahmed S, Madé B, Ledoux E, Gandolfi JM (2006) Association of hydrogeological factors in temporal variations of fluoride concentration in a crystalline aquifer in India. Environ Geol 50(1):1–11

CAS  Google ScholaTekle-Haimanot R, Melaku Z, Kloos H, Reimann C, Fantaye W, Zerihun L, Bjorvatn K (2006) The geographic distribution of fluoride in surface and groundwater in Ethiopia with an emphasis on the Rift Valley. Sci Total Environ 367(1):182–190

CAS  Google Scholar

Tseng WP (1977) Effects and dose-response relationships of skin cancer and blackfoot disease with arsenic. Environ Health Perspect 19:109–119

CAS  Google Scholar

Tseng WP, Chu H, How SW, Fong JM, Lin CS, Yeh SHU (1968) Prevalence of skin cancer in an endemic area of chronic arsenicism in Taiwan 2. J Natl Cancer Inst 40(3):453–463

CAS  Google Scholar

Valenzuela-Vasquez L, Ramirez-Hernandez J, Reyes-Lopez J, Sol-Uribe A, Lazaro-Mancilla O (2006) The origin of fluoride in groundwater supply to Hermosillo City, Sonora, Mexico. Environ Geol 51(1):17–27

CAS  Google Scholar

Villalobos M, Trotz MA, Leckie JO (2001) Surface complexation modeling of carbonate effects on the adsorption of Cr (VI), Pb (II), and U (VI) on goethite. Environ Sci Technol 35(19):3849–3856

CAS  Google Scholar

Wang CH, Hsiao CK, Chen CL, Hsu LI, Chiou HY, Chen SY, Hsueh YM, Wu MM, Chen CJ (2007) A review of the epidemiologic literature on the role of environmental arsenic exposure and cardiovascular diseases. Toxicol Appl Pharmacol 222(3):315–326

Google Scholar

WHO (2017) Guidelines for drinking-water quality: fourth edition incorporating the first addendum. World Health Organization, Geneva Retrieved from https://apps.who.int/iris/ handle/10665/254637 (Licence: CC BY-NC-SA 3.0 IGO). Accessed May 2017

Google Scholar

Wondwossen F, Åstrøm AN, Bjorvatn K, Bårdsen A (2004) The relationship between dental caries and dental fluorosis in areas with moderate- and high-fluoride drinking water in Ethiopia. Community Dent Oral Epidemiol 32(5):337–344

Google Scholar

World Health Organisation (2006) Fluorides in drinking-water. In: Bailey K, Chilton J, Dahi E, Lennon M, Jackson P, Fawell J (eds) WHO drinking-water quality series. IWA Publishing, London

Google Scholar

Yamauchi H, Yamamura Y (1983) Concentration and chemical species of arsenic in human tissue. Bull Environ Contam Toxicol 31(3):267–270

CAS  Google Scholar

Yoder KM, Mabelya L, Robison VA, Dunipace AJ, Brizendine EJ, Stookey GK (1998) Severe dental fluorosis in a Tanzanian population consuming water with negligible fluoride concentration. Community Dent Oral Epidemiol 26(6):382–393

CAS  Google Scholar

Zaldívar R (1974) Arsenic contamination of drinking water and foodstuffs causing endemic chronic poisoning. Beitr Pathol 151(4):384–400

Google Scholar

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