Forty male students were each exposed on two occasions to four hours of inhalation of either air or 500 ppm nitrous oxide with or without 15 ppm halothane in air. Immediately following exposure, a battery of tests of perceptual, cognitive and motor skills was administered. Compared with responses after breathing of air, those after exposure to nitrous oxide and halothane showed significant decrements in performances of a task in which attention was divided between auditory and visual signals, a visual tachistoscopic test, and memory tests involving digit span and recall of word pairs. Subjects exposed to nitrous oxide alone scored
significantly lower on the digit-span test only.
(Key words: Anesthetics, Volatile: halothane; Anesthetics, gases: nitrous oxide; Psychologic function.)
1. Linde HV, Bruce DL: Occupational exposure of anesthetists to halothane. nitrous oxide and radiation. Anesthesiology 30:363-368, 1969.
2. Corbett TH: Retention of anesthetic agents following occupational exposure. Anestl, Analg (Cleve) 52:614-Gli, 1973.
3. Salvini M, Binaschi S, Riva M: Evaluation of the psychophysiological functions in humans exposed to trichloroethylene. Br J Ind Med 28:293-295, 1971.
4. Bruce DL: A simple way to vent anesthetic gases. Anesth Analg (Cleve) 52:595-598, 197.3
Chronic aluminum fluoride administration. I. Behavioral observations
This study examined the behavioral effects of chronic ingestion of various monofluoroaluminum complexes (AlF3) in drinking water. Forty young adult male Long-Evans rats were divided into four groups of 10 rats each. The groups received different concentrations of AlF3 in the drinking water from three sample solutions having a total
Relationship between dental fluorosis and intelligence quotient of school going children in and around Lucknow district: a cross-sectional study
Background: Fluoridation of drinking water, despite being regarded as one of the top ten public health achievements of the twentieth century, has remained a much debated concept. Various studies on animals and aborted human fetuses have confirmed that excessive fluoride intake during infancy and early childhood, causes a number of
Effects of fluoride on learning and memory and cholinesterase activity in rat brains.
Objective: To study the role of fluorosis on learning and memory in rat and its possible mechanisms; to explore the correlation between cholinesterase activity and the level of intelligence. Methods: SD rats divides into 3 group of stochastically according to the sex and the body weight, control group treated with
Exposure to fluoridated water and attention deficit hyperactivity disorder prevalence among children and adolescents in the United States: an ecological association
Background: Epidemiological and animal-based studies have suggested that prenatal and postnatal fluoride exposure has adverse effects on neurodevelopment. The aim of this study was to examine the relationship between exposure to fluoridated water and Attention-Deficit Hyperactivity Disorder (ADHD) prevalence among children and adolescents in the United States. Methods: Data on ADHD
Evaluation of standardized Bacopa monniera extract in sodium fluoride-induced behavioural, biochemical, and histopathological alterations in mice
Effect of standardized Bacopa monniera (BM; family: Scrophulariaceae) extract (100 and 300 mg/kg) against sodium fluoride (NaF; 100 and 200 ppm)-induced behavioural, biochemical, and neuropathological alterations in mice was evaluated. Akinesia, rotarod (motor coordination), forced swim test (depression), open field test (anxiety), transfer latency (memory), cholinesterase (ChE), and oxidative stress
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