Abstract
Objective: To observe the clinical characteristics of occupational chronic fluorosis cases and follow up patients?condition changes after they have been transferred from fluoride work.
Methods: In January 2020, the clinical data of occupational chronic fluorosis cases diagnosed in our hospital and their corresponding two-year follow-up data were collected and analyzed. These cases happened in an aluminum factory between January 2010 to January 2020.
Results: Nine patients were diagnosed as occupational chronic mild fluorosis because of long bones and joints pain. Skeletal X-ray examination showed a result of skeletal fluorosis and increased urine fluoride. Among the six patients who have been followed up for two years, two of them showed improvements in both symptoms and skeletal X-ray examination results. Three patients?symptoms were alleviated, but their skeletal X-ray examination results showed no significant change. Besides them, the last patient?s symptoms and skeletal X-ray examination results were aggravated, which was considered related to still exposed to hydrogen fluoride in new position.
Conclusion: Changes of skeletal X-ray examination are the characteristics of occupational chronic fluorosis. By leaving the fluoride position, patients?clinical symptoms can be alleviated, and their bone lesions are not aggravated or even show a trend of alleviating in some cases.
*Original abstract online at https://pubmed.ncbi.nlm.nih.gov/34218562/
-
-
Effects of water improvement and defluoridation on fluorosis-endemic areas in China: A meta-analysis.
Highlights The first analysis of the effect of improving water quality and reducing fluoride in China over 40 years. Analysis of the effect of water improvement and fluoride reduction in different provinces of China. We analyzed the effect of water improvement on dental fluorosis, skeletal fluorosis, and fluoride content
-
Skeletal fluorosis in Vavuniya District: an observational study.
Background: The WHO recommended safe upper limit for fluoride in drinking water is 1.5 mg/l. Groundwater sources in many parts of Sri Lanka often exceed this limit. The high fluoride content of groundwater and high environmental temperatures in Vavuniya District predispose to pre-skeletal fluorosis and skeletal fluorosis in adults. Objectives: To
-
Efficacy of Calcium-Containing Eggshell Powder Supplementation on Urinary Fluoride and Fluorosis Symptoms in Women in the Ethiopian Rift Valley.
Dietary calcium binds Fluoride (F), thus preventing excess F absorption. We aimed to assess the efficacy of supplementing calcium-containing Eggshell Powder (ESP) on F absorption using urine F excretion and on fluorosis symptoms. In total, 82 women (41 Intervention Group, IG; 41 Control Group, CG) were recruited; overall, 39 in
-
Reversibility of skeletal fluorosis.
At two x ray examinations in 1957 and 1967, 17 cases of skeletal fluorosis were identified among long term cryolite workers in Copenhagen. In 1982 four of these patients were alive, eight to 15 years after exposure had ended. Radiographs were obtained, and the urinary fluoride excretion was measured. A
-
An Outbreak of Industrial Fluorosis in Cattle.
IT may be recalled that in the "Discussion on Fluorosis in Man and Animals" by this Section in February 19411 the occurrence of severe fluorosis in cattle was described on farms in the vicinity of brickworks in Bedfordshire. The purpose of the present communication is to report a similar occurrence
Related Studies :
-
-
-
Variability in Radiographic Appearance of Skeletal Fluorosis
Osteosclerosis (dense bone) is the bone change typically associated with skeletal fluorosis, particularly in the axial skeleton (spine, pelvis, and ribs). Research shows, however, that skeletal fluorosis produces a spectrum of bone changes, including osteomalacia, osteoporosis, exostoses, changes resulting from secondary hyperparathyroidism, and combinations thereof. Although the reason for this radiographic variability is not yet fully understood, it is believed to relate to the dose of fluoride consumed, the individual's nutritional status, exposure to aluminum, genetic susceptibility, presence of kidney disease, and area of the skeleton examined.
-
Skeletal Fluorosis: The Misdiagnosis Problem
It is a virtual certainty that there are individuals in the general population unknowingly suffering from some form of skeletal fluorosis as a result of a doctor's failure to consider fluoride as a cause of their symptoms. Proof that this is the case can be found in the following case reports of skeletal fluorosis written by doctors in the U.S. and other western countries. As can be seen, a consistent feature of these reports is that fluorosis patients--even those with crippling skeletal fluorosis--are misdiagnosed for years by multiple teams of doctors who routinely fail to consider fluoride as a possible cause of their disease.
-
"Pre-Skeletal" Fluorosis
As demonstrated by the studies below, skeletal fluorosis may produce adverse symptoms, including arthritic pains, clinical osteoarthritis, gastrointestinal disturbances, and bone fragility, before the classic bone change of fluorosis (i.e., osteosclerosis in the spine and pelvis) is detectable by x-ray. Relying on x-rays, therefore, to diagnosis skeletal fluorosis will invariably fail to protect those individuals who are suffering from the pre-skeletal phase of the disease. Moreover, some individuals with clinical skeletal fluorosis will not develop an increase in bone density, let alone osteosclerosis, of the spine. Thus, relying on unusual increases in spinal bone density will under-detect the rate of skeletal fluoride poisoning in a population.
-
Fluoride & Osteoarthritis
While the osteoarthritic effects that occurred from fluoride exposure were once considered to be limited to those with skeletal fluorosis, recent research shows that fluoride can cause osteoarthritis in the absence of traditionally defined fluorosis. Conventional methods used for detecting skeletal fluorosis, therefore, will fail to detect the full range of people suffering from fluoride-induced osteoarthritis.
-
Fluoride Reduces Bone Strength Prior to Onset of Skeletal Fluorosis
The majority of animal studies investigating fluoride's impact on bone strength have found that fluoride has either no effect, or a detrimental effect, on bone strength. Importantly, several of the animal studies that have found fluoride reductes bone strength have reported that this reduction in strength occurs before signs of skeletal fluorosis
Related FAN Content :
-