1. Thirty-nine pharmaceuticals prescribed by obstetricians and pediatricians were analyzed
for micro quantities of fluoride for this report,
2. Effect of ingestion of occult fluoride on cord blood and placenta is referred to,
3. Cause of “idiopathic opacities” of enamel and enamel hypoplasias occurring in fluoride free or “optimum supplied” water supplies is suggested.
Ingestion of fluorides for the partial prevention of dental caries has been suggested for some time, with stress laid on the fluoride content of potable water supplies and foods.1-5 Little or no reference has been made to ingestion of the element or its derivatives from other sources, particularly vitamin and mineral supplements prescribed by obstetricians during pregnancy and by pediatricians during infancy and childhood.
In our study,6 which has been under way for more than six years, we have encountered fluoride concentrations in cord blood and placental tissues from control cases which were unexp1ainably high7 because the patient had no known source of fluoride other than that usually found in the dietary, the water being fluoride free. This led us to do micro determinations of fluoride content of pharmaceuticals prescribed by the obstetricians treating the individual cases.
Fluoride metabolism and fluorosis.
OBJECTIVES: This paper is primarily concerned with the only proven risk associated with water fluoridation: enamel fluorosis. Its purpose is to review current methods of measuring enamel fluorosis, its aetiology and metabolism. A further objective is to identify risk factors to reduce the prevalence of enamel fluorosis and employ methods
Fluoride Revolution and Dental Caries: Evolution of Policies for Global Use.
Epidemiological studies over 70 y ago provided the basis for the use of fluoride in caries prevention. They revealed the clear relation between water fluoride concentration, and therefore fluoride exposure, and prevalence and severity of dental fluorosis and dental caries. After successful trials, programs for water fluoridation were introduced, and
Fluoride supplementation (with tablets, drops, lozenges or chewing gum) in pregnant women for preventing dental caries in the primary teeth of their children.
Authors' conclusions: There is no evidence that fluoride supplements taken by women during pregnancy are effective in preventing dental caries in their offspring. Background: Dental caries (tooth decay) is one of the most common chronic childhood diseases. Caries prevalence in most industrialised countries has declined among children over the past few decades. The
Clinical trial of the effect of prenatal fluoride supplements in preventing dental caries.
In 1966 the US Food and Drug Administration forbad advertisements claiming efficacy of prenatal fluoride supplements, due to lack of clinical data supporting such a claim. In the early 1980s, the NIDR funded a randomized clinical trial to address this issue. 1,400 women in the first trimester of pregnancy were
Sources of fluoride intake in children
Wide variations in fluoride intake among children make estimating fluoride intake difficult. This paper discusses the various sources of fluoride intake among children, beginning with a review of the fluoride concentrations of water and other beverages, foods, and therapeutic fluoride products. A review of previous studies' estimates of fluoride intake from diet, dentifrice, fluoride supplements, fluoride mouthrinses, and gels, as well as total fluoride intake also is
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Another Fluoride Fatality: A Physician's Dilemma
Why do physicians fail to correctly evaluate the toxicity of fluoride? Most textbooks rely on the now outdated views of Smith and Hodge who 25 years ago designated 5 to 10 g of fluoride the fatal toxic dose.
Physician's Desk Reference: Fluoride Hypersensitivity
The following are excerpts from various editions of the Physicians' Desk Reference (PDR). "In hypersensitive individuals, fluorides occasionally cause skin eruptions such as atopic dermatitis, eczema or urticaria. Gastric distress, headache and weakness have also been reported. These hypersensitivity reactions usually disappear promptly after discontinuation of the fluoride. In rare cases,
Allergy to Fluoride
Six children and one adult exhibited various allergic reactions after the use of toothpaste and vitaimin preparations containing fluoride. The following conditions were encountered: Urticaria, exfoliative dermatitis, atopic dermatitis, stomatitis, gastro-intestinal and respiratory allergy.
Exposure Pathways Linked to Skeletal Fluorosis
Excessive fluoride exposure from any source -- and from all sources combined -- can cause skeletal fluorosis. Some exposure pathways , however, have been specifically identified as placing individuals at risk of skeletal fluorosis. These exposure pathways include: Fluoridated Water for Kidney Patients Excessive Tea Consumption High-Fluoride Well Water Industrial Fluoride Exposure Fluorinated Pharmaceuticals (Voriconazole
Prenatal and postnatal ingestion of fluorides - A progress report.
The cases described indicate that certain patients react unfavorably to fluoride therapy. Whether the fluorine acts as an allergen after short term use or whether the fluorine acts as an intoxicant after many months of use, is unknown and should be determined.
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