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Placental transfer of fluoride and calcium.
| American Journal of Obstetrics and Gynecology | Armstrong WD, Singer L, Makowski EL. | 107(3):432-434.
Placental transfer Pregnant women Serum-F Tissue F Levels Total Body Burden Urine-F Human Study
References 1.Bawden J.W., Wolkoff A.S., Flowers Jr., C.E. PLACENTAL TRANSFER OF F18 IN SHEEP.  J. Dent. Res. 1964; 43: 678. 2. Clark E.P., Collip J.B. J. A STUJ;)Y OF THE TISDALL METHOD FOR THE DETERMINATION OF BLOOD SERUM CALCIUM WITH A SUGGESTED MODIFICATIONBiol. Chem. 1925; 63: 461. - Full Text PDF 3. Denzer B.S., Reiner M., Weiner S.B. Amer. J. Dis. Child. 1939; 57: 809. Google Scholar 4. Gedalia I., Bryzezinski A., Bercovici B., Lazaron E. ed. 2. Proc. Soc. Exp. Biol. Med

Abstract

Maternal (uterine) artery, maternal (uterine) vein, umbilical artery, and umbilical vein blood were obtained simultaneously at the time of 16 cesarean sections. Calcium determinations of these blood plasma samples and those from women in their ninth month of pregnancy suggest either that a calcium “pump” operates in the placenta supplying a higher concentration of calcium to the fetal blood supply than is found in the maternal circulation or that the calcium homeostatic mechanisms operate at different levels in the maternal and fetal organisms. The fluoride concentrations found in the blood plasmas suggest that the placental barrier to the transport of fluoride ion does not operate so as to maintain a difference in concentration of fluoride between the maternal and fetal body fluids.

Article Info

This work was supported by Grant DE-1850 from the National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland.

*Original abstract online at https://www.ajog.org/article/0002-9378(70)90571-5/fulltext

 

References

1.Bawden J.W., Wolkoff A.S., Flowers Jr., C.E. PLACENTAL TRANSFER OF F18 IN SHEEP.  J. Dent. Res. 1964; 43: 678.

2. Clark E.P., Collip J.B. J. A STUJ;)Y OF THE TISDALL METHOD FOR THE DETERMINATION OF BLOOD SERUM CALCIUM WITH A SUGGESTED MODIFICATIONBiol. Chem. 1925; 63: 461. – Full Text PDF

3. Denzer B.S., Reiner M., Weiner S.B. Amer. J. Dis. Child. 1939; 57: 809. Google Scholar

4. Gedalia I., Bryzezinski A., Bercovici B., Lazaron E. ed. 2. Proc. Soc. Exp. Biol. Med. 106. 1961: 147. Google Scholar

5. Gittleman I.F., Pincus J.B., Schmerzler E., Saito M. Hypocalcemia occurring on the first day of life in mature and premature infants. Pediatrics. 1956; 18: 721.

6. Mull J.W. VARIATIONS IN SERUM CALCIUM AND PHOSPHORUS DURING PREGNANCY. III. THE EFFECT ON THE FETAL CIRCULATION. J. Clin. Invest. 1936; 15: 513.

7. Newman R.L. Further observations on serum calcium and phosphorus in pregnancy. Amer. J. Obstet. Gynec. 1953; 65: 796.

8. Saville P.D., Kretchmer N. Neonatal tetany: a report of 125 cases and review of the literature. Biol. Neonat. 1960; 2: 1.

9. Singer Leon, Armstrong W.D., Colman L.M. MICRODETERMINATION OF CALCIUM IN BIOLOGICAL MATERIALS. Anal. Biochem. 1964; 9: 217.

10. Singer Leon, Armstrong W.D. Anal. Biochem. 1965; 10: 495. Google Scholar

11. Singer Leon, Armstrong W.D. Anal. Biochem. 1965; 10: 495. Google Scholar

12. Taves D.R. Determination of submicromolar concentrations of fluoride in biological samples. Talanta. 1968; 15: 1015.

13. Zettner Alfred, Selegsin David. APPLICATION OF ATOMIC ABSORPTION SPECTROPHOTOMETRY IN THE DETERMINATION OF CALCIUM IN SERUM. Clin. Chem. 1964; 10: 869.

14. Zipkin I., Babeaux W.L. MATERNAL TRANSFER OF FLUORIDE. J. Oral Ther. 1965; 1: 652.

*Original abstract online at https://www.ajog.org/article/0002-9378(70)90571-5/fulltext