A group (I) of 7–12-yr-old children from non-fluoridated communities who had ingested 0.5 mg F supplement/day from shortly after birth to the age of 3 yr. and 1 mg/day thereafter was compared with a control group (II) from the same communities and with a group (III) with lifetime exposure to fluoridated water. The mean DFS scores of Groups I, II and III were approximately in the ratios 1:5:2. A corresponding proportionality was found for the dfs scores. Analyses of enamel biopsies from permanent teeth showed that the mean F concentrations of the surface enamel ranked as follows: Group 1 > Group III > Group II. The prevalence of atypically shallow pits and fissures ranked in the same order. It is concluded, therefore, that the caries-preventive effect of the ingested F was related both to elevated F levels in the surface enamel and to less retentive pits and fissures. Sixty-seven per cent of Group I was classified as having fluorosis mainly of the very mild and mild types; in no case was there any discolouring or pitting of the enamel.
*Original abstract online at https://www.sciencedirect.com/science/article/abs/pii/0003996974901940?via%3Dihub
*See funding for this study at https://europepmc.org/article/MED/12692915
R. Aasenden et al. Evaluation of biopsy data in human enamel fluoride studies. Archs oral Biol. (1971)
R. Aasenden et al. Effects of daily rinsing and ingestion of fluoride solutions upon dental caries and enamel fluoride. Archs oral Biol. (1972)
F. Brudevold et al. An enamel biopsy method for determination of fluoride in human teeth. Archs oral Biol. (1968)
H.R. Englander et al. The Aurora-Rockford, Ill., Study I. Effects of water having natural fluoride on dental health of young adults. J. Am. dent. Ass. (1962)
J.C. Greene et al. The oral hygiene index: a method for classifying oral hygiene status. J. Am. dent. Ass. (1960)
L. Hamberg. Controlled trial of fluoride in vitamin drops for prevention of caries in children. The Lancet (1971)
J.S. Walker et al. Water intake of normal children. Science (1963)
W.J. Simpson et al. A study of crown morphology of newly-erupted first permanent molars in Wetaskiwin, Alberta (optimum fluoride) and Camrose, Alberta (low fluoride). Odont. Revy (1969)
S. Poulsen et al. Anvendelsen af fluortabletter i cariesprofylaksen. Tandlaegebladet (1969)
T.C. Peebles et al. Preventive pediatrics and dental caries control: a twelve-year study of sodium fluoride supplementation
B.J. Orban, I.J. Møller, F.J. McClure. Ingestion of fluoride and dental caries—quantitative relations based on food and water requirements of children 1 to 12 years old. Am. J. Dis. Child. (1943)
Assessing Fluorosis Incidence in Areas with Low Fluoride Content in the Drinking Water, Fluorotic Enamel Architecture, and Composition Alterations.
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Risk of enamel fluorosis in nonfluoridated and optimally fluoridated populations: considerations for the dental professional.
BACKGROUND: Few studies have evaluated the impact of specific fluoride sources on the prevalence of enamel fluorosis in the population. The author conducted research to determine attributable risk percent estimates for mild-to-moderate enamel fluorosis in two populations of middle-school-aged children. METHODS: The author recruited two groups of children 10 to 14
Potential fluoride exposure from selected food crops grown in high fluoride soils in the Makueni County, south-eastern Kenya.
Makueni County, located in south-eastern Kenya, faces challenges such as limited potable water and restricted food supplies as the result of semi-aridity. High fluoride (F) concentrations have been reported in drinking water with resultant dental fluorosis affecting the local population. To determine the potential F exposure through the consumption of
Filled dietary fluoride supplement prescriptions for Medicaid-enrolled children living in states with high and low water fluoridation coverage.
BACKGROUND: Although dietary fluoride (F) supplements (DFS) are recommended for children who use F-deficient drinking water, no studies have examined filled DFS prescriptions across multiple states to examine the dosage consistency with current recommendations or prescription length. METHODS: This sequential cross-sectional analysis used Medicaid claims data for children aged 0.5 through
Evaluation of a fluorosis prevention educational program: A randomized field trial.
Background: A 2-group randomized field trial was conducted to evaluate the impact of a fluorosis educational preventive program in mother´s knowledge and practices, and on the urine fluoride concentration of their preschool children. Material and Methods: A group of 139 mother-child pairs participated in the study. Randomly, children were assigned to an intervention
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Fluoridation of drinking water and chronic kidney disease: Absence of evidence is not evidence of absence
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Mayo Clinic: Fluoridation & Bone Disease in Renal Patients
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Annapolis: Water Fluoridation Linked to Death of Dialysis Patient
EVENING CAPITAL (Annapolis, Maryland) November 29, 1979 Fluoride Linked to Death by Mary Ann Kryzankowicz Staff Writer Fluoride poisoning has been definitely linked to the death of a 65-year-old kidney dialysis patient who became ill during a blood cleaning process Nov 11. State Medical Examiner Dr. (illegible) Guard has ruled that Lawrence Blake, 65, of Arundel
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