The aim of this study was to determine any existing difference in the amount of fluoride incorporated in the surface, body enamel and dentin of two groups of deciduous teeth, either exposed to pre- and postnatal fluoride supplements or to postnatal fluoride only. One hundred and eighty five subjects with intact deciduous incisors were selected from a randomized, double blind study of the caries preventive efficacy of prenatal fluoride (F) supplementation. Surface and body enamel samples were obtained by the acid etch biopsy technique. Dentin microsamples were obtained by drilling to a depth of 100 microm using the microdrill biopsy technique. It was concluded that fluoride exposure during the prenatal period offered no additional measurable fluoride uptake by dental tissues other than that attributable to postnatal fluoride alone.
NIDCR NIH HHS (1)
Arch Oral Biol, (11):929-933 1992
Eur J Oral Sci, (5 Pt 2):461-465 1997
Title not supplied
A review of clinical research on the use of prenatal fluoride administration for prevention of dental caries.
ASDC J Dent Child, (2):109-117 1981
J Dent Res, (5):761-765 1969
Adv Dent Res, (2):168-176 1989
ASDC J Dent Child, (5):317-321 1997
Enamel-fluoride levels in deciduous and permanent teeth of children in high, medium and low fluoride areas.
Arch Oral Biol, (7):423-426 1986
Caries Res, (3):262-265 1985
Distribution of fluoride in the dental tissues and their supporting mandibular bone from the same individual.
Arch Oral Biol, (6):535-537 1994
[Effect of pre- and postnatal fluoride burdens on the fluoride content of the deciduous tooth enamel].
Zahn Mund Kieferheilkd Zentralbl, (1):3-9 1985
Randomized clinical trial of the effect of prenatal fluoride supplements in preventing dental caries.
Caries Res, (3):174-179 1997
Chemical and X-ray analysis of fluoride, phosphorus, and calcium in human foetal blood and hard tissues.
Arch Oral Biol, (12):1169-1178 1996
An in vivo investigation of the fluoride uptake in partially demineralized human enamel from several different dentifrices.
J Dent Res, (1):19-23 1985
Caries Res, (1):44-57 1971
ASDC J Dent Child, (2):128-133 1981
Nature, (5167):582-583 1968
J Dent Res, 742-50; discussion 820-3 1990
US Food and Drug Administration: Statements of General Policy on Interpretation, Oral Prenatal Drugs Containing Fluorides for Human Use. Federal Register, Oct 20, 1966.
Arch Oral Biol, (1):85-97 1967