Showing 1 to 10 of 221 Search Results:
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Prolonged exposure to high fluoride levels during adolescence to adulthood elicits molecular, morphological, and functional impairments in the hippocampus
Bittencourt LO, Dionizio A, Ferreira MKM, Aragão WAB, Cartágenes SDC, Puty B, Maia CDSF, Zohoori FV, Buzalaf MAR, Lima RR
Journal Name: Scientific Reports
Publish Date: July 8, 2023
Volume/Page: Vol 13
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Hippocampus
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Prolonged Fluoride Exposure Induces Spatial-memory Deficit and Hippocampal Dysfunction by Inhibiting Small Heat Shock Protein 22 in Mice
Xin J, Zhu B, Wang H, Zhang Y, Sun N, Cao X, Zheng L, Zhou Y, Fang J, Jing B, Pan K, Zeng Y, Zeng D, Li F, Xia Y, Xu P, Ni X
Journal Name: Journal of Hazardous Materials
Publish Date: May 7, 2023
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Hippocampus, Visual-Spatial Ability
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Sodium Butyrate Ameliorates Fluorosis-Induced Neurotoxicity by Regulating Hippocampal Glycolysis In Vivo.
Li Y., Wang Z., Li J., Yu Y., Wang Y., Jin X., Dong Y., Liu Q., Duan X., Yan N.
Journal Name: Biological Trace Element Research
Publish Date: January 30, 2023
Volume/Page: Online ahead of print
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Dental Fluorosis, Hippocampus
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Systematic impacts of fluoride exposure on the metabolomics of rats.
Zhao S, Guo J, Xue H, Meng J, Xie D, Liu X, Yu Q, Zhong H, Jiang P.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: July 21, 2022
Volume/Page: 242:113888.
Type: Animal Study
Categories: Bones/Joints, Skeletal Fluorosis, Brain, Brain Cellular/Tissue Effects, Dental Fluorosis, Heart, Kidney, Liver, Mechanisms of Cellular Toxicity, Oxidative Stress, Total Body Burden, Tissue F Levels, Hippocampus, Serum-F
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Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway.
Li W, Lu L, Zhu D, Liu J, Shi Y, Zeng H, Yu X, Guo J, Wei B, Cai Y, Sun M.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: May 25, 2022
Volume/Page: 239:113682.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Hippocampus, Animal offspring, Developmental neurotoxicant, Neurotoxicity, Pregnant animal
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Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity.
Han X, Tang Y, Zhang Y, Zhang J, Hu Z, Xu W, Xu S, Niu Q.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: April 11, 2022
Volume/Page: 236:113500.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus, Autophagy, Neurotoxicity, Protective effect
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Evaluation of Metformin and Dehydrozingerone against fluorosis induced neurodevelopmental toxicity in preclinical models.
Ahuja T, Kumar N, Begum F, Shenoy RR.
Journal Name: Alzheimers Dementia
Publish Date: December 31, 2021
Volume/Page: Suppl 12:e058668.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Hippocampus, Lipid peroxidation, Protective effect
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Sirt3-mediated mitochondrial dysfunction is involved in fluoride-induced cognitive deficits.
Wang D, Cao L, Pan S, Wang G, Wang L, Cao N, Hao X.
Journal Name: Food and Chemical Toxicology
Publish Date: November 12, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Mechanisms of Cellular Toxicity, Oxidative Stress, Hippocampus, mitochondrial dysfunction, Neurotoxicity, Sirt3
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Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.
Zhou G, Hu Y, Wang A, Guo M, Du Y, Gong Y, Ding L, Feng Z, Hou X, Xu K, Yu F, Li Z, Ba Y.
Journal Name: Journal of Agricultural and Food Chemistry
Publish Date: November 4, 2021
Volume/Page: [Epub ahead of print]
Type: Animal Study, Cell Study
Categories: Brain, Behavior, Brain Cellular/Tissue Effects, Mechanisms of Cellular Toxicity, Apoptosis, Hippocampus
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Probiotic alleviate fluoride-induced memory impairment by reconstructing gut microbiota in mice.
Xin J, Wang H, Sun N, Bughio S, Zeng D, Li L, Wang Y, Khalique A, Zeng Y, Pan K, Jing B, Ma H, Bai Y, Ni X.
Journal Name: Ecotoxicology and Environmental Safety
Publish Date: March 30, 2021
Volume/Page: 215:112108.
Type: Animal Study
Categories: Brain, Brain Cellular/Tissue Effects, Cognitive Function, Gastrointestinal, Hippocampus, Protective effect